Yuichi Taniguchi
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Explore the profile of Yuichi Taniguchi including associated specialties, affiliations and a list of published articles.
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19
Citations
1115
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Recent Articles
1.
Kim S, Kamarulzaman L, Taniguchi Y
Proc Jpn Acad Ser B Phys Biol Sci
. 2023 Sep;
99(8):306-327.
PMID: 37673661
Studying the central dogma at the single-cell level has gained increasing attention to reveal hidden cell lineages and functions that cannot be studied using traditional bulk analyses. Nonetheless, most single-cell...
2.
Oveisi M, Shukla M, Seymen N, Ohno M, Taniguchi Y, Nahata S, et al.
Bioinformatics
. 2021 Oct;
37(23):4562-4563.
PMID: 34623394
Motivation: Deciphering nucleosome-nucleosome interactions is an important step toward mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available. Results: We developed iNucs, a...
3.
Ohno M, Ando T, Priest D, Taniguchi Y
Nat Protoc
. 2021 May;
16(7):3439-3469.
PMID: 34050337
The nucleosome is the basic organizational unit of the genome. The folding structure of nucleosomes is closely related to genome functions, and has been reported to be in dynamic interplay...
4.
Shinkai S, Nakagawa M, Sugawara T, Togashi Y, Ochiai H, Nakato R, et al.
NAR Genom Bioinform
. 2021 Feb;
2(2):lqaa020.
PMID: 33575580
Genomes are spatiotemporally organized within the cell nucleus. Genome-wide chromosome conformation capture (Hi-C) technologies have uncovered the 3D genome organization. Furthermore, live-cell imaging experiments have revealed that genomes are functional...
5.
BHi-Cect: a top-down algorithm for identifying the multi-scale hierarchical structure of chromosomes
Kumar V, Leclerc S, Taniguchi Y
Nucleic Acids Res
. 2020 Feb;
48(5):e26.
PMID: 32009153
High-throughput chromosome conformation capture (Hi-C) technology enables the investigation of genome-wide interactions among chromosome loci. Current algorithms focus on topologically associating domains (TADs), that are contiguous clusters along the genome...
6.
Leclerc S, Arntz Y, Taniguchi Y
J Vis Exp
. 2019 May;
(146).
PMID: 31058902
Cell proteomes are often characterized using electrophoresis assays, where all species of proteins in the cells are non-specifically labeled with a fluorescent dye and are spotted by a photodetector following...
7.
Ohno M, Ando T, Priest D, Kumar V, Yoshida Y, Taniguchi Y
Cell
. 2019 Jan;
176(3):520-534.e25.
PMID: 30661750
Elucidating the global and local rules that govern genome-wide, hierarchical chromatin architecture remains a critical challenge. Current high-throughput chromosome conformation capture (Hi-C) technologies have identified large-scale chromatin structural motifs, such...
8.
Leclerc S, Arntz Y, Taniguchi Y
Bioconjug Chem
. 2018 Jul;
29(8):2541-2549.
PMID: 29975043
Fluorescence-based electrophoresis has been widely used for proteome analysis in which every protein species in cells is labeled with a fluorescent dye, separated by electric migration, and quantified using fluorescence...
9.
Ohno M, Priest D, Taniguchi Y
Biochem Soc Trans
. 2018 Apr;
46(3):491-501.
PMID: 29626147
Nucleosomes are the unitary structures of chromosome folding, and their arrangements are intimately coupled to the regulation of genome activities. Conventionally, structural analyses using electron microscopy and X-ray crystallography have...
10.
Priest D, Tanaka N, Tanaka Y, Taniguchi Y
Sci Rep
. 2017 Dec;
7(1):17750.
PMID: 29269838
High-throughput microscopy of bacterial cells elucidated fundamental cellular processes including cellular heterogeneity and cell division homeostasis. Polydimethylsiloxane (PDMS)-based microfluidic devices provide advantages including precise positioning of cells and throughput, however...