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Simon G Williams

Explore the profile of Simon G Williams including associated specialties, affiliations and a list of published articles. Areas
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Articles 109
Citations 2076
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Recent Articles
1.
Smith T, Kopajtich R, Demain L, Rea A, Thomas H, Schiff M, et al.
Am J Hum Genet . 2024 Dec; 112(1):59-74. PMID: 39701103
The mitochondrial ribosome (mitoribosome) synthesizes 13 protein subunits of the oxidative phosphorylation system encoded by the mitochondrial genome. The mitoribosome is composed of 12S rRNA, 16S rRNA, and 82 mitoribosomal...
2.
Harrison C, Frain S, Jalalinajafabadi F, Williams S, Keavney B
Heart . 2024 Oct; 110(23):1372-1380. PMID: 39393905
Background: Studies predating widespread COVID-19 vaccination identified patients with congenital heart disease (CHD) as a group at increased risk of severe outcomes from COVID-19. Here we evaluate the impact of...
3.
Smith T, Kopajtich R, Demain L, Rea A, Thomas H, Schiff M, et al.
medRxiv . 2024 Oct; PMID: 39371131
The mitoribosome synthesizes 13 protein subunits of the oxidative phosphorylation system encoded by the mitochondrial genome. The mitoribosome is composed of 12S rRNA, 16S rRNA and 82 mitoribosomal proteins encoded...
4.
Lamprou V, Williams S, Alamgir R, Callan P
Oxf Med Case Reports . 2024 Aug; 2024(8):omae087. PMID: 39161848
No abstract available.
5.
Lee M, Petrie M, Cleland J, Donnelly P, Francis M, Hannah A, et al.
Eur J Heart Fail . 2024 Jul; 26(10):2293-2295. PMID: 39078467
No abstract available.
6.
Black N, Bradley J, Schelbert E, Bonnett L, Lewis G, Lagan J, et al.
J Cardiovasc Magn Reson . 2024 Jul; 26(2):101064. PMID: 39053856
Background: Heart failure (HF) most commonly occurs in patients who have had a myocardial infarction (MI), but factors other than MI size may be deterministic. Fibrosis of myocardium remote from...
7.
Soltani F, Jenkins D, Kaura A, Bradley J, Black N, Farrant J, et al.
BMC Cardiovasc Disord . 2024 Jul; 24(1):343. PMID: 38969974
Background: Heart failure (HF) with preserved or mildly reduced ejection fraction includes a heterogenous group of patients. Reclassification into distinct phenogroups to enable targeted interventions is a priority. This study...
8.
Monaghan R, Naylor R, Flatman D, Kasher P, Williams S, Keavney B
Cardiovasc Res . 2024 May; 120(10):1164-1176. PMID: 38713105
Aims: Rare, deleterious genetic variants in FLT4 are associated with Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease. The distinct genetic variants in FLT4 are also an...
9.
Soltani F, Bradley J, Bonandi A, Black N, Farrant J, Pailing A, et al.
ESC Heart Fail . 2024 Jan; 11(2):1022-1029. PMID: 38232976
Aims: Population-wide, person-level, linked electronic health record data are increasingly used to estimate epidemiology, guide resource allocation, and identify events in clinical trials. The accuracy of data from NHS Digital...
10.
Williams S, Frain S, Guo H, Carr M, Ashcroft D, Keavney B
Open Heart . 2023 Dec; 10(2). PMID: 38097365
Objective: To determine the magnitude of any excess risk of mortality and hospitalisation due to COVID-19 infection in patients with congenital heart disease (CHD) in the UK healthcare system. Methods:...