Silvia Truffa
Overview
Explore the profile of Silvia Truffa including associated specialties, affiliations and a list of published articles.
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16
Citations
666
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Recent Articles
1.
Gude N, Joyo E, Toko H, Quijada P, Villanueva M, Hariharan N, et al.
Basic Res Cardiol
. 2015 Apr;
110(3):29.
PMID: 25893875
Phase I clinical trials applying autologous progenitor cells to treat heart failure have yielded promising results; however, improvement in function is modest, indicating a need to enhance cardiac stem cell...
2.
Khan M, Mohsin S, Toko H, Alkatib M, Nguyen J, Truffa S, et al.
Mol Ther
. 2013 Sep;
22(1):178-85.
PMID: 24002692
Stem cell survival and retention in myocardium after injury following adoptive transfer is low. Elevated catecholamine levels coinciding with myocardial injury adversely affect cardiac progenitor cell (CPC) survival. The G...
3.
Mohsin S, Khan M, Toko H, Bailey B, Cottage C, Wallach K, et al.
J Am Coll Cardiol
. 2012 Jul;
60(14):1278-87.
PMID: 22841153
Objectives: The goal of this study was to demonstrate the enhancement of human cardiac progenitor cell (hCPC) reparative and regenerative potential by genetic modification for the treatment of myocardial infarction....
4.
Di Rocco G, Gentile A, Antonini A, Truffa S, Piaggio G, Capogrossi M, et al.
Cell Transplant
. 2012 Apr;
21(9):1997-2008.
PMID: 22469297
Presently, orthotopic liver transplant is the major therapeutic option for patients affected by primary liver diseases. This procedure is characterized by major invasive surgery, scarcity of donor organs, high costs,...
5.
Massimi I, Guerrieri F, Petroni M, Veschi V, Truffa S, Screpanti I, et al.
Mol Carcinog
. 2012 Mar;
52(7):526-34.
PMID: 22389255
Reactivation of the HMGA1 protoncogene is very frequent in human cancer, but still very little is known on the molecular mechanisms leading to this event. Prompted by the finding of...
6.
Avitabile D, Bailey B, Cottage C, Sundararaman B, Joyo A, McGregor M, et al.
Proc Natl Acad Sci U S A
. 2011 Mar;
108(15):6145-50.
PMID: 21444791
Nucleolar stress, characterized by loss of nucleolar integrity, has not been described in the cardiac context. In addition to ribosome biogenesis, nucleoli are critical for control of cell proliferation and...
7.
Avitabile D, Crespi A, Brioschi C, Parente V, Toietta G, Devanna P, et al.
Am J Physiol Heart Circ Physiol
. 2011 Mar;
300(5):H1875-84.
PMID: 21357510
The efficacy of cardiac repair by stem cell administration relies on a successful functional integration of injected cells into the host myocardium. Safety concerns have been raised about the possibility...
8.
Cheng Z, Volkers M, Din S, Avitabile D, Khan M, Gude N, et al.
Eur Heart J
. 2011 Jan;
32(17):2179-88.
PMID: 21228009
Aims: The cascade of events leading to compromised mitochondrial integrity in response to stress is mediated by various combinatorial interactions of pro- and anti-apoptotic molecules. Nur77, an immediate early gene...
9.
Borillo G, Mason M, Quijada P, Volkers M, Cottage C, McGregor M, et al.
Circ Res
. 2010 Mar;
106(7):1265-74.
PMID: 20203306
Rationale: Cardioprotective signaling mediates antiapoptotic actions through multiple mechanisms including maintenance of mitochondrial integrity. Pim-1 kinase is an essential downstream effector of AKT-mediated cardioprotection but the mechanistic basis for maintenance...
10.
Melchionna R, Romani M, Ambrosino V, DArcangelo D, Cencioni C, Porcelli D, et al.
Cardiovasc Res
. 2009 Dec;
86(2):293-301.
PMID: 20007689
Aims: Acidification is associated with a variety of pathological and physiological conditions. In the present study, we aimed at investigating whether acidic pH may regulate endothelial cell (EC) functions via...