Natalie Gude
Overview
Explore the profile of Natalie Gude including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1908
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Recent Articles
1.
Broughton K, Esquer C, Echeagaray O, Firouzi F, Shain G, Ebeid D, et al.
Cardiovasc Res
. 2022 Jul;
119(3):743-758.
PMID: 35880724
Aims: Declining cellular functional capacity resulting from stress or ageing is a primary contributor to impairment of myocardial performance. Molecular pathway regulation of biological processes in cardiac interstitial cells (CICs)...
2.
Esquer C, Echeagaray O, Firouzi F, Savko C, Shain G, Bose P, et al.
Life Sci Alliance
. 2021 Nov;
5(2).
PMID: 34810278
Vaping of flavored liquids has been touted as safe alternative to traditional cigarette smoking with decreased health risks. The popularity of vaping has dramatically increased over the last decade, particularly...
3.
Huang C, Mendez N, Echeagaray O, Weeks J, Wang J, Yao S, et al.
Adv Ther (Weinh)
. 2021 Mar;
3(6).
PMID: 33644299
Mono- or dual-checkpoint inhibitors for immunotherapy have changed the paradigm of cancer care; however, only a minority of patients responds to such treatment. Combining small molecule immuno-stimulators can improve treatment...
4.
Huang C, Mendez N, Echeagaray O, Weeks J, Wang J, Vallez C, et al.
ACS Appl Mater Interfaces
. 2019 Jul;
11(30):26637-26647.
PMID: 31276378
Stimulation of Toll-like receptors (TLRs) and/or NOD-like receptors on immune cells initiates and directs immune responses that are essential for vaccine adjuvants. The small-molecule TLR7 agonist, imiquimod, has been approved...
5.
Wang J, Barback C, Ta C, Weeks J, Gude N, Mattrey R, et al.
IEEE Trans Med Imaging
. 2017 Aug;
37(1):222-229.
PMID: 28829305
An on-demand long-lived ultrasound contrast agent that can be activated with single pulse stimulated imaging (SPSI) has been developed using hard shell liquid perfluoropentane filled silica 500-nm nanoparticles for tumor...
6.
Liu N, Wang B, Broughton K, Alvarez R, Siddiqi S, Loaiza R, et al.
PLoS One
. 2017 Mar;
12(3):e0173963.
PMID: 28323876
PIM1, a pro-survival gene encoding a serine/ threonine kinase, influences cell proliferation and survival. Modification of cardiac progenitor cells (CPCs) or cardiomyocytes with PIM1 using a lentivirus-based delivery method showed...
7.
Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla F, et al.
J Mol Cell Cardiol
. 2016 Oct;
100:54-63.
PMID: 27721024
Background: Myocardial infarction is followed by cardiac dysfunction, cellular death, and ventricular remodeling, including tissue fibrosis. S100A4 protein plays multiple roles in cellular survival, and tissue fibrosis, but the relative...
8.
Doroudgar S, Volkers M, Thuerauf D, Khan M, Mohsin S, Respress J, et al.
Circ Res
. 2015 Jul;
117(6):536-46.
PMID: 26137860
Rationale: Hydroxymethyl glutaryl-coenzyme A reductase degradation protein 1 (Hrd1) is an endoplasmic reticulum (ER)-transmembrane E3 ubiquitin ligase that has been studied in yeast, where it contributes to ER protein quality...
9.
Gude N, Joyo E, Toko H, Quijada P, Villanueva M, Hariharan N, et al.
Basic Res Cardiol
. 2015 Apr;
110(3):29.
PMID: 25893875
Phase I clinical trials applying autologous progenitor cells to treat heart failure have yielded promising results; however, improvement in function is modest, indicating a need to enhance cardiac stem cell...
10.
Volkers M, Doroudgar S, Nguyen N, Konstandin M, Quijada P, Din S, et al.
EMBO Mol Med
. 2014 Jan;
6(1):57-65.
PMID: 24408966
Diabetes is a multi-organ disease and diabetic cardiomyopathy can result in heart failure, which is a leading cause of morbidity and mortality in diabetic patients. In the liver, insulin resistance...