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Silvia Bungaro

Explore the profile of Silvia Bungaro including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 150
Followers 0
Related Specialties
Hematology
Oncology
General Medicine
Top 10 Co-Authors
Giovanni Cazzaniga
Andrea Biondi
Enrico Pogliani
Carlo Gambacorti-Passerini
Pietro Pioltelli
Maurizio DIncalci
Fabio Rossi
Lucia Tornaghi
Bryan D Young
Roberta Frapolli
Published In
Haematologica
Blood Cells Mol Dis
Genes Chromosomes Cancer
PLoS One
Clin Cancer Res
Affiliations
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Recent Articles
1.
Conjoined Genes as Common Events in Childhood Acute Lymphoblastic Leukemia
Severgnini M, DAngio M, Bungaro S, Cazzaniga G, Cifola I, Fazio G
Cancers (Basel) . 2022 Jul; 14(14). PMID: 35884588
Acute lymphoblastic leukemia (ALL) is the most frequent childhood cancer. For the last three decades, conventional cytogenetic and molecular approaches allowed the identification of genetic abnormalities having prognostic and therapeutic...
2.
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia
Fontana D, Ramazzotti D, Aroldi A, Redaelli S, Magistroni V, Pirola A, et al.
Hemasphere . 2020 Nov; 4(6):e497. PMID: 33196013
Atypical chronic myeloid leukemia (aCML) is a -negative clonal disorder, which belongs to the myelodysplastic/myeloproliferative group. This disease is characterized by recurrent somatic mutations in , and genes, as well...
3.
Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival
Salmoiraghi S, Guinea Montalvo M, Ubiali G, Tosi M, Peruta B, Zanghi P, et al.
Haematologica . 2016 Mar; 101(6):e245-8. PMID: 26992948
No abstract available.
4.
The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia
Casolaro A, Golay J, Albanese C, Ceruti R, Patton V, Cribioli S, et al.
PLoS One . 2013 Mar; 8(3):e58424. PMID: 23520509
CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We describe the establishment and characterisation of a novel...
5.
A de novo supernumerary genomic discontinuous ring chromosome 21 in a child with mild intellectual disability
Villa N, Bentivegna A, Ertel A, Redaelli S, Colombo C, Nacinovich R, et al.
Am J Med Genet A . 2011 May; 155A(6):1425-31. PMID: 21574245
Small supernumerary marker chromosomes (sSMCs) are structurally abnormal extra chromosomes that cannot be unambiguously identified or characterized by conventional banding techniques alone, and they are generally equal in size or...
6.
ETV6-RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis
Emerenciano M, Bungaro S, Cazzaniga G, Dorea M, Coser V, Magalhaes I, et al.
Cancer Genet Cytogenet . 2009 Aug; 193(2):86-92. PMID: 19665068
Acute lymphoblastic leukemia (ALL) in infants is characterized by a high frequency of MLL gene rearrangements. By contrast, the t(12;21) ETV6-RUNX1 fusion gene is typically detected in children older than...
7.
Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks
Bungaro S, Campo DellOrto M, Zangrando A, Basso D, Gorletta T, Lo Nigro L, et al.
Genes Chromosomes Cancer . 2008 Sep; 48(1):22-38. PMID: 18803328
Pediatric acute lymphoblastic leukemia (ALL) comprises genetically distinct subtypes. However, 25% of cases still lack defined genetic hallmarks. To identify genomic aberrancies in childhood ALL patients nonclassifiable by conventional methods,...
8.
Assessment of submicroscopic genetic lesions by single nucleotide polymorphism arrays in a child with acute myeloid leukemia and FLT3-internal tandem duplication
Bungaro S, Raghavan M, DellOro M, Paolucci P, Young B, Biondi A, et al.
Haematologica . 2006 Jun; 91(7):998-1000. PMID: 16757411
The same FLT3-internal tandem duplication (ITD) positive clone was detected at diagnosis and relapse, but not at birth, in a child with M1 acute myeloid leukemia. Single nucleotide polymorphism arrays...
9.
Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients
Gambacorti-Passerini C, Zucchetti M, Russo D, Frapolli R, Verga M, Bungaro S, et al.
Clin Cancer Res . 2003 Feb; 9(2):625-32. PMID: 12576428
Purpose: Imatinib (Glivec) is a potent inhibitor of bcr/abl, an oncogenic fusion protein that causes chronic myelogenous leukemia (CML). alpha1 acid glycoprotein (AGP) binds to imatinib with high affinity and...
10.
Differences between in vivo and in vitro sensitivity to imatinib of Bcr/Abl+ cells obtained from leukemic patients
Gambacorti-Passerini C, Rossi F, Verga M, Ruchatz H, Gunby R, Frapolli R, et al.
Blood Cells Mol Dis . 2002 Oct; 28(3):361-72. PMID: 12367580
Imatinib mesylate (imatinib) inhibits Bcr/Abl, an oncogenic fusion protein. The in vitro effects of imatinib on BCR/ABL+ leukemic cells include inhibition of Bcr/Abl tyrosine phosphorylation, block of proliferation, and induction...