Sigvard Olofsson
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Explore the profile of Sigvard Olofsson including associated specialties, affiliations and a list of published articles.
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40
Citations
898
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Recent Articles
1.
Bagdonaite I, Marinova I, Rudjord-Levann A, Pallesen E, King-Smith S, Karlsson R, et al.
Nat Commun
. 2023 Nov;
14(1):7000.
PMID: 37919266
Viral and host glycans represent an understudied aspect of host-pathogen interactions, despite potential implications for treatment of viral infections. This is due to lack of easily accessible tools for analyzing...
2.
Olofsson S, Bally M, Trybala E, Bergstrom T
Annu Rev Virol
. 2023 Jun;
10(1):283-304.
PMID: 37285578
N- and O-glycans are both important constituents of viral envelope glycoproteins. O-linked glycosylation can be initiated by any of 20 different human polypeptide O-acetylgalactosaminyl transferases, resulting in an important functional...
3.
Abidine Y, Liu L, Wallen O, Trybala E, Olofsson S, Bergstrom T, et al.
Viruses
. 2022 Aug;
14(8).
PMID: 36016458
The diffusion of viruses at the cell membrane is essential to reach a suitable entry site and initiate subsequent internalization. Although many viruses take advantage of glycosaminoglycans (GAG) to bind...
4.
Norden R, Nilsson J, Samuelsson E, Risinger C, Sihlbom C, Blixt O, et al.
Int J Mol Sci
. 2019 Mar;
20(4).
PMID: 30813247
A recombinant subunit vaccine (Shingrix) was recently licensed for use against herpes zoster. This vaccine is based on glycoprotein E (gE) of varicella zoster virus (VZV), the most abundantly expressed...
5.
Delguste M, Peerboom N, Le Brun G, Trybala E, Olofsson S, Bergstrom T, et al.
ACS Chem Biol
. 2019 Feb;
14(3):534-542.
PMID: 30735356
Mucin-like regions, characterized by a local high density of O-linked glycosylation, are found on the viral envelope glycoproteins of many viruses. Herpes simplex virus type 1 (HSV-1), for example, exhibits...
6.
Risinger C, Sorensen K, Jensen K, Olofsson S, Bergstrom T, Blixt O
ACS Infect Dis
. 2017 Feb;
3(5):360-367.
PMID: 28238255
Detection of type-specific antibodies is an important and essential part of accurate diagnosis, even in silent carriers of herpes simplex virus (HSV)-1 (oral) and HSV-2 (genital) infections. Serologic assays that...
7.
Bagdonaite I, Norden R, Joshi H, King S, Vakhrushev S, Olofsson S, et al.
J Biol Chem
. 2016 Apr;
291(23):12014-28.
PMID: 27129252
Herpesviruses are among the most complex and widespread viruses, infection and propagation of which depend on envelope proteins. These proteins serve as mediators of cell entry as well as modulators...
8.
Olofsson S, Blixt O, Bergstrom T, Frank M, Wandall H
Rev Med Virol
. 2015 Nov;
26(1):34-48.
PMID: 26524377
Viral envelope glycoproteins are major targets for antibodies that bind to and inactivate viral particles. The capacity of a viral vaccine to induce virus-neutralizing antibodies is often used as a...
9.
High Cytokine Levels in Tonsillitis Secretions Regardless of Presence of Beta-Hemolytic Streptococci
Skovbjerg S, Roos K, Olofsson S, Lindh M, Ljung A, Hynsjo L, et al.
J Interferon Cytokine Res
. 2015 Jun;
35(9):682-9.
PMID: 26060912
Acute pharyngotonsillitis denotes tonsillar inflammation caused by bacteria or viruses. Here, we investigated if beta-hemolytic streptococci (β-HS) tonsillitis would differ in inflammatory mediator response from tonsillitis of other causes. Tonsillar...
10.
Norberg P, Lindh M, Olofsson S
BMC Infect Dis
. 2015 Apr;
15:162.
PMID: 25887656
Background: Tamiflu (oseltamivir phosphate ester, OE) is a widely used antiviral active against influenza A virus. Its active metabolite, oseltamivir carboxylate (OC), is chemically stable and secreted into wastewater treatment...