Siegfried Wolffram
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Explore the profile of Siegfried Wolffram including associated specialties, affiliations and a list of published articles.
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71
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Recent Articles
11.
Wein S, Beyer B, Gohlke A, Blank R, Metges C, Wolffram S
PLoS One
. 2016 Jul;
11(7):e0159428.
PMID: 27427946
Green tea catechins have various potential health benefits in humans including anti-inflammatory, anti-oxidative and hepato-protective effects. If present in the circulation, they might have similar effects in ruminants, which are...
12.
Brull V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Muller C, et al.
Eur J Nutr
. 2016 Jul;
56(7):2265-2275.
PMID: 27423432
Purpose: Chronic low-level systemic and adipose tissue inflammation has been identified as a major etiologic factor in many chronic diseases, including hypertension and cardiovascular diseases. Evidence from experimental studies suggests...
13.
Brull V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Muller C, et al.
Eur J Nutr
. 2016 Mar;
56(3):1347-1357.
PMID: 26924303
Purpose: To determine whether postprandial metabolic and vascular responses induced by a high-fat and high-carbohydrate meal are attenuated by ingestion of the flavonol quercetin. Methods: Twenty-two overweight-to-obese hypertensive patients participated...
14.
Stoldt A, Derno M, Das G, Weitzel J, Wolffram S, Metges C
J Dairy Sci
. 2016 Jan;
99(3):2161-2168.
PMID: 26805964
Flavonoids are secondary plant metabolites with several health promoting effects. As dairy cows often suffer from metabolic imbalance and health problems, interest is growing in health improvements by plant substances...
15.
Gruse J, Kanitz E, Weitzel J, Tuchscherer A, Stefaniak T, Jawor P, et al.
PLoS One
. 2016 Jan;
11(1):e0146932.
PMID: 26752173
Immaturity of the neonatal immune system is causative for high morbidity in calves and colostrum intake is crucial for acquiring passive immunity. Pathogenesis is promoted by reactive oxygen species accumulating...
16.
Burak C, Brull V, Langguth P, Zimmermann B, Stoffel-Wagner B, Sausen U, et al.
Eur J Nutr
. 2015 Oct;
56(1):343-353.
PMID: 26482244
Purpose: To investigate the plasma kinetics of quercetin derived from hard capsules filled with onion skin extract powder or quercetin dihydrate in humans. Methods: In a randomized, single-blind, diet-controlled crossover...
17.
Wein S, Laviano A, Wolffram S
J Nutr Biochem
. 2015 Oct;
26(12):1660-3.
PMID: 26432773
Exogenous factors such as food components including the flavonoid quercetin are suspected to influence micro RNA (miRNA) concentrations and thus possibly target enzymes involved in xenobiotic metabolism. This study therefore...
18.
Gruse J, Gors S, Tuchscherer A, Otten W, Weitzel J, Metges C, et al.
J Nutr
. 2015 Sep;
145(11):2486-95.
PMID: 26400967
Background: Inadequate colostrum supply results in insufficient intake of macronutrients and bioactive factors, thereby impairing gastrointestinal development and the maturation of glucose metabolism in neonatal calves. The flavonoid quercetin has...
19.
Brull V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Muller C, et al.
Br J Nutr
. 2015 Sep;
114(8):1263-77.
PMID: 26328470
The polyphenol quercetin may prevent CVD due to its antihypertensive and vasorelaxant properties. We investigated the effects of quercetin after regular intake on blood pressure (BP) in overweight-to-obese patients with...
20.
Nguyen M, Staubach P, Wolffram S, Langguth P
J Pharm Sci
. 2015 May;
104(9):3199-207.
PMID: 25988261
Quercetin is a plant flavonol that is available from both daily diet and nutraceuticals. To investigate the effect of acute and short-term intake of high-dose quercetin on CYP3A-mediated metabolism, 10...