Siegfried Roth
Overview
Explore the profile of Siegfried Roth including associated specialties, affiliations and a list of published articles.
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61
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2126
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Recent Articles
1.
Roth S
Annu Rev Cell Dev Biol
. 2023 Oct;
39:1-22.
PMID: 37843930
Toll signaling plays a crucial role in pathogen defense throughout the animal kingdom. It was discovered, however, for its function in dorsoventral (DV) axis formation in . In all other...
2.
Jacobs C, van der Hulst R, Chen Y, Williamson R, Roth S, van der Zee M
Philos Trans R Soc Lond B Biol Sci
. 2022 Oct;
377(1865):20210266.
PMID: 36252212
Insects comprise more than a million species and many authors have attempted to explain this success by evolutionary innovations. A much overlooked evolutionary novelty of insects is the serosa, an...
3.
Pers D, Buchta T, Ozuak O, Roth S, Lynch J
J Dev Biol
. 2022 Feb;
10(1).
PMID: 35225961
The Toll signaling pathway is the main source of embryonic DV polarity in the fly This pathway appears to have been co-opted from an ancestral innate immunity system within the...
4.
Du E, Wang S, Luan Y, Zhou C, Li Z, Li N, et al.
Mol Biol Evol
. 2022 Feb;
39(3).
PMID: 35192709
Insects have evolved numerous adaptations and colonized diverse terrestrial environments. Several polyneopterans, including dictyopterans (cockroaches and mantids) and locusts, have developed oothecae, but little is known about the molecular mechanism,...
5.
Hakeemi M, Ansari S, Teuscher M, Weisskopf M, Grossmann D, Kessel T, et al.
BMC Biol
. 2022 Feb;
20(1):38.
PMID: 35135533
Background: Most of the known genes required for developmental processes have been identified by genetic screens in a few well-studied model organisms, which have been considered representative of related species,...
6.
Luo W, Liu S, Zhang W, Yang L, Huang J, Zhou S, et al.
Proc Natl Acad Sci U S A
. 2021 Sep;
118(39).
PMID: 34544864
It is well documented that the juvenile hormone (JH) can function as a gonadotropic hormone that stimulates vitellogenesis by activating the production and uptake of vitellogenin in insects. Here, we...
7.
Pechmann M, Kenny N, Pott L, Heger P, Chen Y, Buchta T, et al.
Elife
. 2021 Mar;
10.
PMID: 33783353
Dorsoventral pattering relies on Toll and BMP signalling in all insects studied so far, with variations in the relative contributions of both pathways. and the beetle share extensive dependence on...
8.
Herndon N, Shelton J, Gerischer L, Ioannidis P, Ninova M, Donitz J, et al.
BMC Genomics
. 2020 Jan;
21(1):47.
PMID: 31937263
Background: The red flour beetle Tribolium castaneum has emerged as an important model organism for the study of gene function in development and physiology, for ecological and evolutionary genomics, for...
9.
Benton M, Frey N, da Fonseca R, von Levetzow C, Stappert D, Hakeemi M, et al.
Elife
. 2019 Oct;
8.
PMID: 31573513
The Fog pathway represents one of the best-understood signaling cascades controlling epithelial morphogenesis. During gastrulation, Fog induces apical cell constrictions that drive the invagination of mesoderm and posterior gut primordia....
10.
Panfilio K, Vargas Jentzsch I, Benoit J, Erezyilmaz D, Suzuki Y, Colella S, et al.
Genome Biol
. 2019 Apr;
20(1):64.
PMID: 30935422
Background: The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology and excellent experimental tractability for molecular genetics. Building upon recent sequencing...