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Orhan Ozuak

Explore the profile of Orhan Ozuak including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 117
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Recent Articles
1.
Pers D, Buchta T, Ozuak O, Roth S, Lynch J
J Dev Biol . 2022 Feb; 10(1). PMID: 35225961
The Toll signaling pathway is the main source of embryonic DV polarity in the fly This pathway appears to have been co-opted from an ancestral innate immunity system within the...
2.
Pechmann M, Kenny N, Pott L, Heger P, Chen Y, Buchta T, et al.
Elife . 2021 Mar; 10. PMID: 33783353
Dorsoventral pattering relies on Toll and BMP signalling in all insects studied so far, with variations in the relative contributions of both pathways. and the beetle share extensive dependence on...
3.
Pers D, Buchta T, Ozuak O, Wolff S, Pietsch J, Memon M, et al.
BMC Biol . 2016 Aug; 14:63. PMID: 27480122
Background: Gene regulatory networks (GRNs) underlie developmental patterning and morphogenetic processes, and changes in the interactions within the underlying GRNs are a major driver of evolutionary processes. In order to...
4.
Ozuak O, Buchta T, Roth S, Lynch J
Curr Biol . 2014 Oct; 24(20):2393-8. PMID: 25308075
In Drosophila, Toll signaling leads to a gradient of nuclear uptake of Dorsal with a peak at the ventral egg pole and is the source for dorsoventral (DV) patterning and...
5.
Ozuak O, Buchta T, Roth S, Lynch J
Dev Genes Evol . 2014 Oct; 224(4-6):223-33. PMID: 25304164
The transforming growth factor beta (TGF)-β signaling pathway and its modulators are involved in many aspects of cellular growth and differentiation in all metazoa. Although most of the core components...
6.
Buchta T, Ozuak O, Stappert D, Roth S, Lynch J
Dev Biol . 2013 Jun; 381(1):189-202. PMID: 23735637
Regulatory networks composed of interacting genes are responsible for pattern formation and cell type specification in a wide variety of developmental contexts. Evolution must act on these regulatory networks in...
7.
Lynch J, Ozuak O, Khila A, Abouheif E, Desplan C, Roth S
PLoS Genet . 2011 May; 7(4):e1002029. PMID: 21552321
The establishment of the germline is a critical, yet surprisingly evolutionarily labile, event in the development of sexually reproducing animals. In the fly Drosophila, germ cells acquire their fate early...