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Siddharth Subham

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Articles 7
Citations 61
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Recent Articles
1.
Akhavan D, Subham S, Jeppson J, Aguilar B, Wong R, Hibbard J, et al.
Cells . 2024 Jul; 13(13. PMID: 38994929
Standard-of-care treatment for Glioblastoma Multiforme (GBM) is comprised of surgery and adjuvant chemoradiation. Chimeric Antigen Receptor (CAR) T cell therapy has demonstrated disease-modifying activity in GBM and holds great promise....
2.
Subham S, Jeppson J, Gibbs B, Babai J, Alker R, Godwin A, et al.
J Vis Exp . 2023 Nov; (200). PMID: 37955379
Chimeric antigen receptor (CAR) T cells are at the forefront of oncology. A CAR is constructed of a targeting domain (usually a single chain variable fragment, scFv), with an accompanying...
3.
Subham S, Jeppson J, Worcester C, Schatmeyer B, Zhao J, Madan R, et al.
Breast Cancer Res Treat . 2022 Nov; 197(1):57-69. PMID: 36318382
Purpose: There is currently no curative treatment for patients diagnosed with triple-negative breast cancer brain metastases (TNBC-BM). CAR T cells hold potential for curative treatment given they retain the cytolytic...
4.
Pacelli S, Paolicelli P, Petralito S, Subham S, Gilmore D, Varani G, et al.
ACS Appl Bio Mater . 2022 Jan; 3(2):945-951. PMID: 35019296
Gellan gum-based hydrogels display limited cell adhesion ability due to the absence of cell-anchorage points usually present in proteins found in the extracellular matrix (ECM). This issue limits their use...
5.
Pacelli S, Chakravarti A, Modaresi S, Subham S, Burkey K, Kurlbaum C, et al.
J Biomed Mater Res A . 2021 Jun; 109(12):2597-2610. PMID: 34189837
Hydrogels can be fabricated and designed to exert direct control over stem cells' adhesion and differentiation. In this study, we have investigated the use of polydopamine (pDA)-treatment as a binding...
6.
Waters R, Subham S, Pacelli S, Modaresi S, Chakravarti A, Paul A
Mol Pharm . 2019 Aug; 16(10):4302-4312. PMID: 31398053
Secretome-based therapies have the potential to become the next generation of viable therapeutic wound repair treatments. However, precise strategies aimed to refine and control the secretome composition are necessary to...
7.
Pacelli S, Rampetsreiter K, Modaresi S, Subham S, Chakravarti A, Lohfeld S, et al.
ACS Appl Mater Interfaces . 2018 Jul; 10(30):24955-24962. PMID: 29969894
Hydrogel surface properties can be modified to form bioactive interfaces to modulate the osteogenic differentiation of stem cells. In this work, a hydrogel made of gelatin methacrylamide (GelMA) and alginate...