» Authors » Settimio Pacelli

Settimio Pacelli

Explore the profile of Settimio Pacelli including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 35
Citations 556
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Modaresi S, Pacelli S, Chakraborty A, Coyle A, Luo W, Singh I, et al.
Adv Healthc Mater . 2024 Aug; 13(29):e2401264. PMID: 39152923
Human adipose-derived stem cells (hASCs) are cryopreserved traditionally using dimethyl sulfoxide (DMSO) as the cryoprotectant agent. DMSO penetrates cell membranes and prevents cellular damage during cryopreservation. However, DMSO is not...
2.
Acosta F, Pacelli S, Rathbone C
PLoS One . 2023 Aug; 18(8):e0289477. PMID: 37540699
The skeletal muscles of Type II diabetic (T2D) patients can be characterized by a reduced vessel density, corresponding to deficiencies in microvascular angiogenesis. Interestingly, T2D also inhibits the function of...
3.
Acosta F, Gonzalez Porras M, Stojkova K, Pacelli S, Rathbone C, Brey E
J Vis Exp . 2023 Feb; (192). PMID: 36806034
Engineering thermogenic adipose tissue (e.g., beige or brown adipose tissues) has been investigated as a potential therapy for metabolic diseases or for the design of personalized microtissues for health screening...
4.
Chakraborty A, Pacelli S, Alexander S, Huayamares S, Rosenkrans Z, Vergel F, et al.
Mol Pharm . 2022 Nov; 20(1):767-774. PMID: 36322617
Natural polymer-based hydrogels are excellent for encapsulating hydrophilic drugs, but they are mechanically weak and degrade easily. In this communication, we exploit the electrostatic interaction between nanosilicates (nSi) and gelatin...
5.
Basu S, Johl R, Pacelli S, Gehrke S, Paul A
ACS Macro Lett . 2022 May; 9(9):1230-1236. PMID: 35638638
This work investigates a sequential strategy to develop DNA-based hydrogel scaffolds with interpenetrating polymeric network. The scaffolds were formed via a two-step procedure. First, a covalently cross-linked DNA-based cryogel was...
6.
Pacelli S, Paolicelli P, Petralito S, Subham S, Gilmore D, Varani G, et al.
ACS Appl Bio Mater . 2022 Jan; 3(2):945-951. PMID: 35019296
Gellan gum-based hydrogels display limited cell adhesion ability due to the absence of cell-anchorage points usually present in proteins found in the extracellular matrix (ECM). This issue limits their use...
7.
Pacelli S, Chakravarti A, Modaresi S, Subham S, Burkey K, Kurlbaum C, et al.
J Biomed Mater Res A . 2021 Jun; 109(12):2597-2610. PMID: 34189837
Hydrogels can be fabricated and designed to exert direct control over stem cells' adhesion and differentiation. In this study, we have investigated the use of polydopamine (pDA)-treatment as a binding...
8.
Chakravarti A, Pacelli S, Paul A
Nanoscale . 2020 Dec; 12(47):24273-24284. PMID: 33295935
Prevailing drug delivery strategies rely on the use of synthetic nanocarriers like metal nanoparticles and polymeric liposomes to control the release of therapeutics in a safe and efficacious manner. Despite...
9.
Pacelli S, Di Muzio L, Paolicelli P, Fortunati V, Petralito S, Trilli J, et al.
Int J Biol Macromol . 2020 Nov; 166:1292-1300. PMID: 33161086
Cryogels are a particular type of hydrogels that possess great potential in both fields of drug delivery and tissue engineering. Based on these premises, the goal of this work was...
10.
Acosta F, Jia U, Stojkova K, Howland K, Guda T, Pacelli S, et al.
Tissue Eng Part A . 2020 Sep; 27(9-10):549-560. PMID: 32878567
Skeletal muscle is a tissue that is directly involved in the progression and persistence of type 2 diabetes (T2D), a disease that is becoming increasingly common. Gaining better insight into...