Siddharth S Dey
Overview
Explore the profile of Siddharth S Dey including associated specialties, affiliations and a list of published articles.
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23
Citations
805
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Recent Articles
1.
Bond A, Fiaz S, Rollins K, Nario J, Snyder E, Atkins D, et al.
Dev Cell
. 2024 Aug;
59(21):2882-2896.e7.
PMID: 39137774
Macrophages measure the "eat-me" signal immunoglobulin G (IgG) to identify targets for phagocytosis. We tested whether prior encounters with IgG influence macrophage appetite. IgG is recognized by the Fc receptor....
2.
Chirikian O, Faynus M, Merk M, Singh Z, Muray C, Pham J, et al.
bioRxiv
. 2024 Jun;
PMID: 38895282
Hypertrophy Cardiomyopathy (HCM) is the most prevalent hereditary cardiovascular disease - affecting >1:500 individuals. Advanced forms of HCM clinically present with hypercontractility, hypertrophy and fibrosis. Several single-point mutations in b-myosin...
3.
Chialastri A, Sarkar S, Schauer E, Lamba S, Dey S
Nat Struct Mol Biol
. 2024 Apr;
31(8):1296-1308.
PMID: 38671229
Inheritance of 5-methylcytosine from one cell generation to the next by DNA methyltransferase 1 (DNMT1) plays a key role in regulating cellular identity. While recent work has shown that the...
4.
Atkins D, Rosas J, Mansson L, Shahverdi N, Dey S, Pitenis A
ACS Biomater Sci Eng
. 2024 Mar;
10(4):2177-2187.
PMID: 38466617
Pancreatic ductal adenocarcinoma (PDAC) accounts for about 90% of all pancreatic cancer cases. Five-year survival rates have remained below 12% since the 1970s, in part due to the difficulty in...
5.
Heom K, Wangsanuwat C, Butkovich L, Tam S, Rowe A, OMalley M, et al.
mSystems
. 2023 Oct;
8(6):e0028123.
PMID: 37855606
Microbes present one of the most diverse sources of biochemistry in nature, and mRNA sequencing provides a comprehensive view of this biological activity by quantitatively measuring microbial transcriptomes. However, efficient...
6.
Batjargal T, Zappa F, Grant R, Piscopio R, Chialastri A, Dey S, et al.
Cell Syst
. 2023 Jul;
14(7):551-562.e5.
PMID: 37473728
The integrated stress response (ISR) is a conserved signaling network that detects aberrations and computes cellular responses. Dissecting these computations has been difficult because physical and chemical inducers of stress...
7.
Chialastri A, Sarkar S, Schauer E, Lamba S, Dey S
bioRxiv
. 2023 May;
PMID: 37205524
Transmission of 5-methylcytosine (5mC) from one cell generation to the next plays a key role in regulating cellular identity in mammalian development and diseases. While recent work has shown that...
8.
Chialastri A, Wangsanuwat C, Dey S
STAR Protoc
. 2021 Dec;
2(4):101016.
PMID: 34950891
The asymmetric distribution of 5-hydroxymethylcytosine (5hmC) between two DNA strands of a chromosome enables endogenous reconstruction of cellular lineages at an individual-cell-division resolution. Further, when integrated with data on genomic...
9.
Wangsanuwat C, Chialastri A, Aldeguer J, Rivron N, Dey S
Cell Rep Methods
. 2021 Sep;
1(4).
PMID: 34590075
Lineage reconstruction is central to understanding tissue development and maintenance. To overcome the limitations of current techniques that typically reconstruct clonal trees using genetically encoded reporters, we report scPECLR, a...
10.
Sen M, Mooijman D, Chialastri A, Boisset J, Popovic M, Heindryckx B, et al.
Nat Commun
. 2021 Feb;
12(1):1286.
PMID: 33627650
DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the parental genomes during preimplantation mammalian development is critical to reset the methylome of gametes to...