Si-Han Chen
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Explore the profile of Si-Han Chen including associated specialties, affiliations and a list of published articles.
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51
Citations
771
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Recent Articles
1.
Ruzmetov T, Hung T, Jonnalagedda S, Chen S, Fasihianifard P, Guo Z, et al.
J Chem Inf Model
. 2025 Feb;
65(5):2487-2502.
PMID: 39984300
Proteins are inherently dynamic, and their conformational ensembles play a crucial role in biological function. Large-scale motions may govern the protein structure-function relationship, and numerous transient but stable conformations of...
2.
Wu Y, Liu C, Yan Q, Chen S, Kuang Z, Liu H, et al.
Curr Org Synth
. 2025 Jan;
PMID: 39851107
Nitrogen-containing heterocycles, such as indoles and quinolines, serve as the key scaffolds in numerous pharmaceuticals, pesticides, and natural products. The synthesis methods of nitrogen-containing heterocycles show significant scientific and industrial...
3.
Ji Y, Wang Y, Chen S, Cheng Y
J Alzheimers Dis
. 2024 Dec;
102(4):1017-1026.
PMID: 39660534
Background: Impaired clearance of amyloid-β protein (Aβ) in the peripheral system is a crucial event in the pathogenesis of sporadic Alzheimer's disease (AD). Dysfunctional monocytes with deficient clearance of Aβ...
4.
Ruzmetov T, Hung T, Jonnalagedda S, Chen S, Fasihianifard P, Guo Z, et al.
bioRxiv
. 2024 Jul;
PMID: 38979147
Proteins are inherently dynamic, and their conformational ensembles are functionally important in biology. Large-scale motions may govern protein structure-function relationship, and numerous transient but stable conformations of Intrinsically Disordered Proteins...
5.
Ruzmetov T, Hung T, Jonnalagedda S, Chen S, Fasihianifard P, Guo Z, et al.
Res Sq
. 2024 Jul;
PMID: 38978607
Proteins are inherently dynamic, and their conformational ensembles are functionally important in biology. Large-scale motions may govern protein structure-function relationship, and numerous transient but stable conformations of intrinsically disordered proteins...
6.
Sun P, Liu J, Hu J, Tu Y, Jiang Q, Jia Y, et al.
Sci Adv
. 2024 May;
10(22):eadl1123.
PMID: 38809977
Immunosenescence contributes to systematic aging and plays a role in the pathogenesis of Alzheimer's disease (AD). Therefore, the objective of this study was to investigate the potential of immune rejuvenation...
7.
Gan X, Liu P, Chen S, Li J, Zhao X, Chen W, et al.
Asian J Surg
. 2023 Jul;
47(1):8-15.
PMID: 37419810
Pilonidal sinus is a chronic condition characterized by inflammation, swelling, and pain in the sacrococcygeal region. In recent years, the rate of recurrence and wound complications in PSD remains high,...
8.
Fu X, Zhuo D, Zhang Y, Li Y, Liu X, Xing Y, et al.
Proc Natl Acad Sci U S A
. 2023 Jun;
120(24):e2219649120.
PMID: 37276408
How left-right (LR) asymmetry emerges in a patterning field along the anterior-posterior axis remains an unresolved problem in developmental biology. Left-biased Nodal emanating from the LR organizer propagates from posterior...
9.
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer's disease
Cheng Y, He C, Tian D, Chen S, Ren J, Sun H, et al.
Acta Neuropathol
. 2023 Mar;
145(6):717-731.
PMID: 36964213
Cerebral amyloid-β (Aβ) accumulation due to impaired Aβ clearance is a pivotal event in the pathogenesis of Alzheimer's disease (AD). Considerable brain-derived Aβ is cleared via transporting to the periphery....
10.
Chen S, Xiang X, Che P, Hu B, Shui D, Zhao Y, et al.
J Ultrasound Med
. 2022 Dec;
42(7):1385-1399.
PMID: 36579829
Objective: To evaluate the diagnostic performance of SMI in the diagnosis of benign and malignant breast lesions. Methods: A systematic search of PubMed, EMBASE, Cochrane, OVID, SCI, and SCOPUS was...