Chen-Yang He
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Explore the profile of Chen-Yang He including associated specialties, affiliations and a list of published articles.
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22
Citations
225
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Recent Articles
1.
Peng S, He C, Zhang Q, Wang M, Sheng X, Gao J, et al.
J Psychiatr Res
. 2024 Nov;
168:91-99.
PMID: 39492237
Approximately 90% of adults have ever experienced obsessions, yet less than 3% of them develop OCD. It is hypothesized that excessive fear of negative events contributes to OCD onset and...
2.
Zhao K, Wang X, Shao M, He C, Yuan F
Int J Immunopathol Pharmacol
. 2023 Jul;
37:3946320231184988.
PMID: 37400958
Objectives: This experimental study aims to investigate the role of long noncoding RNA X-inactive specific transcript (lncRNA XIST) in the microglial polarization and microglia-mediated neurotoxicity in Alzheimer's disease (AD). Methods:...
3.
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer's disease
Cheng Y, He C, Tian D, Chen S, Ren J, Sun H, et al.
Acta Neuropathol
. 2023 Mar;
145(6):717-731.
PMID: 36964213
Cerebral amyloid-β (Aβ) accumulation due to impaired Aβ clearance is a pivotal event in the pathogenesis of Alzheimer's disease (AD). Considerable brain-derived Aβ is cleared via transporting to the periphery....
4.
Ren J, Wang Z, Cheng Y, He C, Jian J, Fan D, et al.
J Alzheimers Dis
. 2023 Feb;
92(2):477-485.
PMID: 36776069
Background: The kidney-brain crosstalk has been involved in Alzheimer's disease (AD) with the mechanism remaining unclear. The anti-aging factor Klotho was reported to attenuate both kidney injury and AD pathologies....
5.
He C, Wang Z, Shen Y, Shi A, Li H, Chen D, et al.
CNS Neurosci Ther
. 2022 Sep;
28(12):2218-2229.
PMID: 36074475
Introduction And Aims: Alzheimer's disease (AD) is the most common form of dementia with a complex genetic background. The cause of sporadic AD (sAD) remains largely unknown. Increasing evidence shows...
6.
He C, Tian D, Chen S, Jin W, Cheng Y, Xin J, et al.
Neurosci Bull
. 2022 Aug;
39(2):261-272.
PMID: 35974288
The extracellular domain (p75ECD) of p75 neurotrophin receptor (p75NTR) antagonizes Aβ neurotoxicity and promotes Aβ clearance in Alzheimer's disease (AD). The impaired shedding of p75ECD is a key pathological process...
7.
Cheng Y, Jian J, He C, Ren J, Xu M, Jin W, et al.
J Alzheimers Dis
. 2022 May;
88(1):375-383.
PMID: 35599489
Background: The dysregulation of lipid metabolism plays an important role in the pathogenesis of Alzheimer's disease (AD). Liver-type fatty acid-binding protein (L-FABP, also known as FABP1) is critical for fatty...
8.
Jian J, Fan D, Tian D, Cheng Y, Sun P, Tan C, et al.
Neurosci Bull
. 2022 May;
38(9):1025-1040.
PMID: 35570231
Increased neuronal apoptosis is an important pathological feature of Alzheimer's disease (AD). The Bcl-2-interacting mediator of cell death (Bim) mediates amyloid-beta (Aβ)-induced neuronal apoptosis. Naturally-occurring antibodies against Bim (NAbs-Bim) exist...
9.
Cheng Y, Ren J, Jian J, He C, Xu M, Zeng G, et al.
Transl Psychiatry
. 2022 May;
12(1):194.
PMID: 35538065
Angiostatin, an endogenous angiogenesis inhibitor generated by the proteolytic cleavage of plasminogen, was recently reported to contribute to the development of Alzheimer's disease (AD). However, whether there are pathological changes...
10.
Wang J, Fan D, Li H, He C, Shen Y, Zeng G, et al.
Mol Neurodegener
. 2022 Jan;
17(1):9.
PMID: 35033164
Background: Loss of brain capillary pericyte is involved in the pathologies and cognitive deficits in Alzheimer's disease (AD). The role of pericyte in early stage of AD pathogenesis remains unclear....