Shunsuke Kimura
Overview
Explore the profile of Shunsuke Kimura including associated specialties, affiliations and a list of published articles.
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167
Citations
3978
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Recent Articles
11.
Kinashi Y, Tanaka K, Kimura S, Hirota M, Komiyama S, Shindo T, et al.
EBioMedicine
. 2024 Jul;
106:105256.
PMID: 39059316
Background: Intestinal epithelial cells (IECs) serve as robust barriers against potentially hostile luminal antigens and commensal microbiota. Epithelial barrier dysfunction enhances intestinal permeability, leading to leaky gut syndrome (LGS) associated...
12.
Kiriyama A, Kimura S, Yamashita S
Pharmacol Res Perspect
. 2024 Jul;
12(4):e1249.
PMID: 39017590
This study assessed the pharmacokinetics (PKs) and pharmacodynamics (PDs) of two antihypertensive drugs, nifedipine and captopril, by exploring their main (blood pressure [BP]) and secondary effects (heart rate [HR] and...
13.
Kimura S, Sekine H, Kawasaki T, Sato T, Kasahara N
Dent Mater J
. 2024 Jul;
43(4):552-558.
PMID: 38987203
This study aimed to clarify the fracture resistance of resin abutments built on endodontically treated roots with the remaining coronal teeth via static and cyclic loading tests. Endodontically treated bovine...
14.
Kimura S, Park C, Montefiori L, Iacobucci I, Polonen P, Gao Q, et al.
Cancer Discov
. 2024 Jun;
14(10):1838-1859.
PMID: 38916500
Acute lymphoblastic leukemia expressing the gamma delta T-cell receptor (γδ T-ALL) is a poorly understood disease. We studied 200 children with γδ T-ALL from 13 clinical study groups to understand...
15.
Zhao Z, Song F, Kimura S, Onodera T, Uchida T, Toko K
Molecules
. 2024 Jun;
29(11).
PMID: 38893328
Taste sensors with an allostery approach have been studied to detect non-charged bitter substances, such as xanthine derivatives, used in foods (e.g., caffeine) or pharmaceuticals (e.g., etofylline). In this study,...
16.
Mi T, Soerens A, Alli S, Kang T, Vasandan A, Wang Z, et al.
Nat Aging
. 2024 Jun;
4(8):1053-1063.
PMID: 38867059
Chronological aging correlates with epigenetic modifications at specific loci, calibrated to species lifespan. Such 'epigenetic clocks' appear conserved among mammals, but whether they are cell autonomous and restricted by maximal...
17.
Sumaria N, Fiala G, Inacio D, Curado-Avelar M, Cachucho A, Pinheiro R, et al.
Nat Immunol
. 2024 May;
25(7):1207-1217.
PMID: 38802512
The contribution of γδ T cells to immune responses is associated with rapid secretion of interferon-γ (IFN-γ). Here, we show a perinatal thymic wave of innate IFN-γ-producing γδ T cells...
18.
Yamashita S, Imanishi A, Ueki S, Okamoto S, Kimura S, Kiriyama A
Mol Pharm
. 2024 May;
21(7):3173-3185.
PMID: 38798088
This study aimed to investigate the effect of pH-responsive doxorubicin (DOX) release and the targetability of pilot molecules in folic acid (FA)-modified micelles using a pharmacokinetic-pharmacodynamic (PK-PD) model. The time...
19.
Watanabe K, Tasaka K, Ogata H, Kato S, Ueno H, Umeda K, et al.
Cancer Gene Ther
. 2024 Apr;
31(7):1049-1059.
PMID: 38622340
Novel therapeutic strategies are urgently required for osteosarcoma, given the early age at onset and persistently high mortality rate. Modern transcriptomics techniques can identify differentially expressed genes (DEGs) that may...
20.
Kimura S, Ebihara A, Maki K, Kyaw M, Kasuga Y, Omori S, et al.
J Dent Sci
. 2024 Apr;
19(2):929-936.
PMID: 38618130
Background/purpose: Temperature-dependent phase compositional changes influence the mechanical properties of heat-treated nickel-titanium (NiTi) rotary instruments. This study evaluated the phase composition, bending properties, and cyclic fatigue resistance of HyFlex EDM...