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Shunlin Ren

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Articles 44
Citations 1176
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Recent Articles
1.
Wang Y, Sanyal A, Hylemon P, Ren S
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40047198
Mitochondrial oxysterols, cholestenoic acid (CA), 25-hydroxycholesterol (25HC), and 27-hydroxycholesterol (27HC), are potent regulators involved in many important biological events. This study aimed to investigate the metabolic pathways of these oxysterols...
2.
Wang Y, Ren J, Ren S
Am J Physiol Endocrinol Metab . 2024 Feb; 326(5):E577-E587. PMID: 38381400
Larsucosterol, a potent endogenous epigenetic regulator, has been reported to play a significant role in lipid metabolism, inflammatory responses, and cell survival. The administration of larsucosterol has demonstrated a reduction...
3.
Wang Y, Pandak W, Hylemon P, Min H, Min J, Fuchs M, et al.
Am J Physiol Gastrointest Liver Physiol . 2023 Nov; 326(2):G147-G162. PMID: 37961761
Cholestenoic acid (CA) has been reported as an important biomarker of many severe diseases, but its physiological and pathological roles remain unclear. This study aimed to investigate the potential role...
4.
Liu Y, Tang Y, Ren S, Chen L
Plants (Basel) . 2023 Feb; 12(4). PMID: 36840240
Infectious diseases caused by pathogenic bacteria severely threaten human health. Traditional Chinese herbs are potential sources of new or alternative medicine. In this study, we analyzed for the first time...
5.
Wang Y, Pandak W, Lesnefsky E, Hylemon P, Ren S
Cells . 2021 Nov; 10(11). PMID: 34831255
Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure (ALF). N-acetylcysteine (NAC) is currently being used as part of the standard care in the clinic...
6.
Chen D, Liang Z, Ren S, Alali W, Chen L
J Food Prot . 2021 Aug; 85(1):44-53. PMID: 34436566
Abstract: Vibrio cholerae can cause pandemic cholera in humans. The bacterium resides in aquatic environments worldwide. Continuous testing of V. cholerae contamination in water and aquatic products is imperative for...
7.
Wang Y, Lin W, Brown J, Chen L, Pandak W, Hylemon P, et al.
J Lipid Res . 2021 Mar; 62:100063. PMID: 33705741
The oxysterol sulfate, 25-hydroxycholesterol 3-sulfate (25HC3S), has been shown to play an important role in lipid metabolism, inflammatory response, and cell survival. However, the mechanism(s) of its function in global...
8.
Wang Y, Li X, Ren S
Metabolites . 2020 Dec; 11(1). PMID: 33375700
Oxysterols have long been believed to be ligands of nuclear receptors such as liver × receptor (LXR), and they play an important role in lipid homeostasis and in the immune...
9.
Yang L, Wang Y, Yu P, Ren S, Zhu Z, Jin Y, et al.
Front Cell Infect Microbiol . 2020 Dec; 10:595709. PMID: 33363055
is a leading seafood-borne pathogen that can cause acute gastroenteritis and even death in humans. In aquatic ecosystems, phages constantly transform bacterial communities by horizontal gene transfer. Nevertheless, biological functions...
10.
Wang Y, Chen L, Pandak W, Heuman D, Hylemon P, Ren S
iScience . 2020 May; 23(5):101102. PMID: 32408171
This work investigates the relationship between high-glucose (HG) culture, CpG methylation of genes involved in cell signaling pathways, and the regulation of carbohydrate and lipid metabolism in hepatocytes. The results...