Shulamit Michaeli
Overview
Explore the profile of Shulamit Michaeli including associated specialties, affiliations and a list of published articles.
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95
Citations
2491
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Recent Articles
1.
Rajan K, Aryal S, Hiregange D, Bashan A, Madmoni H, Olami M, et al.
Cell Rep
. 2024 May;
43(5):114203.
PMID: 38722744
Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA, changes during the parasite life cycle. Alterations...
2.
Rajan K, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe Y, et al.
Nat Commun
. 2023 Nov;
14(1):7462.
PMID: 37985661
Trypanosomes are protozoan parasites that cycle between insect and mammalian hosts and are the causative agent of sleeping sickness. Here, we describe the changes of pseudouridine (Ψ) modification on rRNA...
3.
Atari N, Rajan K, Chikne V, Cohen-Chalamish S, Doniger T, Orbaum O, et al.
Viruses
. 2022 Aug;
14(8).
PMID: 36016343
The nucleolus is a subnuclear compartment whose primary function is the biogenesis of ribosomal subunits. Certain viral infections affect the morphology and composition of the nucleolar compartment and influence ribosomal...
4.
Rajan K, Adler K, Doniger T, Cohen-Chalamish S, Aharon-Hefetz N, Aryal S, et al.
J Biol Chem
. 2022 Jun;
298(7):102141.
PMID: 35714765
Trypanosoma brucei, the parasite that causes sleeping sickness, cycles between an insect and a mammalian host. However, the effect of RNA modifications such as pseudouridinylation on its ability to survive...
5.
Guegan F, Rajan K, Bento F, Pinto-Neves D, Sequeira M, Guminska N, et al.
Sci Adv
. 2022 Jun;
8(24):eabn2706.
PMID: 35704590
The parasite causes African sleeping sickness that is fatal to patients if untreated. Parasite differentiation from a replicative slender form into a quiescent stumpy form promotes host survival and parasite...
6.
Piel L, Rajan K, Bussotti G, Varet H, Legendre R, Proux C, et al.
PLoS Pathog
. 2022 Mar;
18(3):e1010375.
PMID: 35294501
The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental...
7.
Bussotti G, Piel L, Pescher P, Domagalska M, Rajan K, Cohen-Chalamish S, et al.
Proc Natl Acad Sci U S A
. 2021 Dec;
118(51).
PMID: 34903666
How genome instability is harnessed for fitness gain despite its potential deleterious effects is largely elusive. An ideal system to address this important open question is provided by the protozoan...
8.
Okalang U, Mualem Bar-Ner B, Rajan K, Friedman N, Aryal S, Egarmina K, et al.
mBio
. 2021 Nov;
12(6):e0260221.
PMID: 34844425
In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are -spliced to generate a common 5' exon derived from the spliced leader (SL) RNA....
9.
Kannan S, Harel Y, Israel L, Lellouche E, Varvak A, Tsubery M, et al.
Bioconjug Chem
. 2021 Oct;
32(11):2327-2341.
PMID: 34664934
Leishmaniasis is among the five parasitic diseases that still require the development of new drugs. Ultrasmall cerium (Ce) cation-doped maghemite (γ-FeO) nanoparticles (NPs) were tested as a potential drug to...
10.
Yariv I, Kannan S, Harel Y, Levy E, Duadi H, Lellouche J, et al.
Biomed Opt Express
. 2021 Aug;
12(7):4496-4509.
PMID: 34457428
Nanoparticles (NPs) based drugs for topical administration are gaining interest in the biomedical world. However, a study tool of their penetration depth to the different tissue layers without additional markers...