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Shukuko Ikawa

Explore the profile of Shukuko Ikawa including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 210
Followers 0
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Recent Articles
1.
Shibata T, Ikawa S, Iwasaki W, Sasanuma H, Masai H, Hirota K
Nucleic Acids Res . 2024 Jan; 52(5):2565-2577. PMID: 38214227
RecA protein and RecA/Rad51 orthologues are required for homologous recombination and DNA repair in all living creatures. RecA/Rad51 catalyzes formation of the D-loop, an obligatory recombination intermediate, through an ATP-dependent...
2.
Konomura N, Arai N, Shinohara T, Kobayashi J, Iwasaki W, Ikawa S, et al.
Nucleic Acids Res . 2016 Oct; 45(1):337-352. PMID: 27794044
RecA-family recombinase-catalyzed ATP-dependent homologous joint formation is critical for homologous recombination, in which RecA or Rad51 binds first to single-stranded (ss)DNA and then interacts with double-stranded (ds)DNA. However, when RecA...
3.
Shinohara T, Ikawa S, Iwasaki W, Hiraki T, Hikima T, Mikawa T, et al.
Nucleic Acids Res . 2015 Jan; 43(2):973-86. PMID: 25561575
In all organisms, RecA-family recombinases catalyze homologous joint formation in homologous genetic recombination, which is essential for genome stability and diversification. In homologous joint formation, ATP-bound RecA/Rad51-recombinases first bind single-stranded...
4.
Nii D, Hayashida T, Yamaguchi Y, Ikawa S, Shibata T, Umemura K
Colloids Surf B Biointerfaces . 2014 Jul; 121:325-30. PMID: 24974776
Single-stranded DNA-binding (SSB) proteins were treated with hybrids of DNA and single-walled carbon nanotubes (SWNTs) to examine the biological function of the DNA molecules adsorbed on the SWNT surface. When...
5.
Morozumi Y, Ino R, Ikawa S, Mimida N, Shimizu T, Toki S, et al.
PLoS One . 2013 Oct; 8(10):e75451. PMID: 24124491
In higher eukaryotes, RAD51 functions as an essential protein in homologous recombination and recombinational repair of DNA double strand breaks. During these processes, RAD51 catalyzes homologous pairing between single-stranded DNA...
6.
Takaku M, Takahashi D, Machida S, Ueno H, Hosoya N, Ikawa S, et al.
Nucleic Acids Res . 2010 Jul; 38(21):7579-86. PMID: 20639531
The human Ena/Vasp-like (EVL) protein is considered to be a bifunctional protein, involved in both actin remodeling and homologous recombination. In the present study, we found that human EVL forms...
7.
Hikiba J, Takizawa Y, Ikawa S, Shibata T, Kurumizaka H
FEBS J . 2008 Dec; 276(2):457-65. PMID: 19076215
The DMC1 protein, a meiosis-specific DNA recombinase, promotes homologous pairing and strand exchange. The I37N single nucleotide polymorphism of the human DMC1 protein was reported as a result of human...
8.
Kagawa W, Kagawa A, Saito K, Ikawa S, Shibata T, Kurumizaka H, et al.
J Biol Chem . 2008 Jul; 283(35):24264-73. PMID: 18593704
Rad52 plays essential roles in homology-dependent double-strand break repair. Various studies have established the functions of Rad52 in Rad51-dependent and Rad51-independent repair processes. However, the precise molecular mechanisms of Rad52...
9.
Sakane I, Kamataki C, Takizawa Y, Nakashima M, Toki S, Ichikawa H, et al.
Nucleic Acids Res . 2008 Jun; 36(13):4266-76. PMID: 18583359
The DMC1 protein, a meiosis-specific DNA recombinase, catalyzes strand exchange between homologous chromosomes. In rice, two Dmc1 genes, Dmc1A and Dmc1B, have been reported. Although the Oryza sativa DMC1A protein...
10.
Hikiba J, Hirota K, Kagawa W, Ikawa S, Kinebuchi T, Sakane I, et al.
Nucleic Acids Res . 2008 Jun; 36(12):4181-90. PMID: 18566005
The M200V polymorphism of the human DMC1 protein, which is an essential, meiosis-specific DNA recombinase, was found in an infertile patient, raising the question of whether this homozygous human DMC1-M200V...