Shuhui Geng
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Explore the profile of Shuhui Geng including associated specialties, affiliations and a list of published articles.
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9
Citations
64
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Recent Articles
1.
Liu Y, Xu Z, Shi J, Zhang Y, Yang S, Chen Q, et al.
iScience
. 2022 Sep;
25(9):105003.
PMID: 36117996
ZFP57 and ZFP445 maintain genomic imprinting in mouse embryos. We found DNA methylation was lost at most examined imprinting control regions (ICRs) in mouse mutant ES cells, which could not...
2.
Xu Z, Shi J, Zhang Y, Liu Y, Zhao J, Chen Q, et al.
Front Cell Dev Biol
. 2022 Mar;
10:784128.
PMID: 35252168
has both maternal and zygotic functions in mouse. It maintains genomic imprinting at most known imprinted regions and controls allelic expression of the target imprinted genes in mouse embryos. The...
3.
Geng S, Lei Y, Snead M
JOM (1989)
. 2021 Aug;
73(6):1696-1704.
PMID: 34456537
Amelogenin is the most abundant matrix protein guiding hydroxyapatite formation in enamel, the durable bioceramic tissue that covers vertebrate teeth. Here, we sought to refine structure-function for an amelogenin domain...
4.
Murad R, Avanes A, Ma X, Geng S, Mortazavi A, Momand J
Gene
. 2021 Jul;
799:145808.
PMID: 34224831
We set out to uncover transcriptome and chromatin landscape changes that occur in HER2 + breast cancer (BC) cells upon acquiring resistance to trastuzumab. RNA-seq analysis was applied to two...
5.
Jiang W, Shi J, Zhao J, Wang Q, Cong D, Chen F, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(5).
PMID: 33500348
ZFP57 is a master regulator of genomic imprinting. It has both maternal and zygotic functions that are partially redundant in maintaining DNA methylation at some imprinting control regions (ICRs). In...
6.
Lenz G, Hamilton A, Geng S, Hong T, Kalkum M, Momand J, et al.
Clin Cancer Res
. 2017 Nov;
24(5):1216-1226.
PMID: 29180608
Increased glycolysis and glucose dependence is a hallmark of malignancy that enables tumors to maximize cell proliferation. In HER2 cancers, an increase in glycolytic capacity is associated with trastuzumab resistance....
7.
Theile D, Geng S, Denny E, Momand J, Kane S
Cell Signal
. 2017 Sep;
40:53-61.
PMID: 28867659
t-Darpp is the truncated form of the dopamine- and cAMP-regulated phosphoprotein of 32kDa (Darpp-32) and has been demonstrated to confer resistance to trastuzumab, a Her2-targeted anticancer agent, via sustained signaling...
8.
Geng S, White S, Paine M, Snead M
J Biol Chem
. 2015 Jun;
290(34):20661-20673.
PMID: 26070558
Enamel is a bioceramic tissue composed of thousands of hydroxyapatite crystallites aligned in parallel within boundaries fabricated by a single ameloblast cell. Enamel is the hardest tissue in the vertebrate...
9.
Zhang W, Sun B, Wang X, Liu J, Zhang Z, Geng S
J Clin Neurosci
. 2010 Jan;
17(3):368-71.
PMID: 20089409
The aims of this study were (1) to evaluate the effect of high-dose erythropoietin (EPO; 5000 U/kg) on expression of inducible nitric oxide synthase (iNOS) in the facial nucleus after...