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Shrikant V Gupte

Explore the profile of Shrikant V Gupte including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 56
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Recent Articles
1.
Bhagwat S, Mundkur L, Gupte S, Patel M, Khorakiwala H
Antimicrob Agents Chemother . 2006 Aug; 50(11):3568-79. PMID: 16940059
WCK 771 is a broad-spectrum fluoroquinolone with enhanced activity against quinolone-resistant staphylococci. To understand the impact of the target-level interactions of WCK 771 on its antistaphylococcal pharmacodynamic properties, we determined...
2.
de Souza N, Gupte S, Deshpande P, Desai V, Bhawsar S, Yeole R, et al.
J Med Chem . 2005 Aug; 48(16):5232-42. PMID: 16078842
There is an urgent medical need for novel antibacterial agents to treat hospital infections, specially those caused by multidrug-resistant Gram-positive pathogens. The need may also be fulfilled by either exploring...
3.
Patel M, de Souza N, Gupte S, Jafri M, Bhagwat S, Chugh Y, et al.
Antimicrob Agents Chemother . 2004 Nov; 48(12):4754-61. PMID: 15561853
WCK 771, the arginine salt of S-(-)-nadifloxacin, was evaluated in animal models of staphylococcal infection and in vitro. For 302 methicillin-susceptible strains the MIC at which 50% of isolates are...
4.
Jacobs M, Bajaksouzian S, Windau A, Appelbaum P, Patel M, Gupte S, et al.
Antimicrob Agents Chemother . 2004 Aug; 48(9):3338-42. PMID: 15328094
The activity of WCK 771, an experimental quinolone developed to overcome quinolone resistance in staphylococci and other bacteria, was determined against quinolone-susceptible and -resistant Staphylococcus aureus and S. epidermidis. WCK...