Mahesh V Patel
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Explore the profile of Mahesh V Patel including associated specialties, affiliations and a list of published articles.
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15
Citations
175
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Recent Articles
1.
Bruno B, Weavil J, Ogle J, Chidambaram N, Carey E, Danford C, et al.
Hepatology
. 2024 Nov;
PMID: 39513970
Background And Aims: Sarcopenia is highly prevalent in patients with liver cirrhosis and is associated with adverse clinical outcomes, including HE. Androgen receptor agonists, androgen receptor agonists, can address these...
2.
Hujer A, Marshall S, Mack A, Hujer K, Bakthavatchalam Y, Umarkar K, et al.
mBio
. 2023 Oct;
14(6):e0111823.
PMID: 37889005
Compared to other genera of Gram-negative pathogens, is adept in acquiring complex non-enzymatic and enzymatic resistance mechanisms thus remaining a challenge to even novel antibiotics including recently developed β-lactam and...
3.
Ahirrao V, Jadhav R, Vaidya S, Bhagwat S, Yeole R, Patel M
Biomed Chromatogr
. 2022 Feb;
36(6):e5354.
PMID: 35141944
Antibiotic susceptibility test (AST) discs are used as an in-vitro diagnostic tool to select the appropriate antibiotic to treat an infection. Generally, the concentration of the drug loaded on to...
4.
DelConte A, Papangkorn K, Kim K, Bruno B, Chidambaram N, Khera M, et al.
Andrology
. 2022 Jan;
10(4):669-676.
PMID: 34994093
Background: Male hypogonadism (testosterone level < 300 ng/dl) is a clinical syndrome that results from failure of the testis to produce physiological levels of testosterone. Most marketed testosterone replacement therapy...
5.
Bhagwat S, Legakis N, Skalidis T, Loannidis A, Goumenopoulos C, Joshi P, et al.
Diagn Microbiol Infect Dis
. 2021 Mar;
100(3):115327.
PMID: 33744624
Cefepime/zidebactam is in clinical development for the treatment of carbapenem-resistant Gram-negative infections. MICs of cefepime/zidebactam (1:1) and comparators against Enterobacterales (n = 563), Pseudomonas (n = 172) and Acinetobacter baumannii...
6.
Albhaisi S, Kim K, Baker J, Chidambaram N, Patel M, Charlton M, et al.
Hepatol Commun
. 2020 Oct;
4(10):1430-1440.
PMID: 33024914
Hypogonadism affects hepatic lipid metabolism and is expected to promote nonalcoholic fatty liver disease (NAFLD). The aims of this study were to determine (1) the prevalence of NAFLD in hypogonadal...
7.
Bhagwat S, Hariharan P, Joshi P, Palwe S, Shrivastava R, Patel M, et al.
J Antimicrob Chemother
. 2020 Aug;
75(12):3563-3567.
PMID: 32772098
Background: Recent reports reveal the emergence of Escherichia coli isolates harbouring a novel resistance mechanism based on four-amino-acid inserts in PBP3. These organisms concomitantly expressed ESBLs or/and serine-/metallo-carbapenemases and were...
8.
Yeole R, Rane V, Ahirrao V, Chavan R, Patel A, Deshpande P, et al.
Biomed Chromatogr
. 2019 Mar;
33(7):e4532.
PMID: 30861568
WCK 771 is an l-arginine salt of levonadifloxacin (LND) being developed in intravenous dosage form and has recently completed a phase III trial in India. The pharmacokinetics of WCK 771,...
9.
Ahirrao V, Rane V, Patil K, Patil V, Yeole R, Patel M
J Chromatogr Sci
. 2018 Jun;
56(9):789-793.
PMID: 29931104
A highly stereo-specific liquid chromatographic method was developed and validated for the quantification of enantiomeric impurity (R-enantiomer) in novel oxazolidinone antibacterial agent (WCK 4086), a drug substance. The separation was...
10.
Papp-Wallace K, Nguyen N, Jacobs M, Bethel C, Barnes M, Kumar V, et al.
J Med Chem
. 2018 Apr;
61(9):4067-4086.
PMID: 29627985
Limited treatment options exist to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria possessing broad-spectrum β-lactamases. The design of novel β-lactamase inhibitors is of paramount importance. Here, three novel diazabicyclooctanes...