Shree Ram Singh
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Explore the profile of Shree Ram Singh including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
1943
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Recent Articles
1.
Aggarwal P, Liu Z, Cheng G, Singh S, Shi C, Chen Y, et al.
Cell Rep
. 2022 Jun;
39(12):110958.
PMID: 35732115
We previously showed that the Arf1-mediated lipolysis pathway sustains stem cells and cancer stem cells (CSCs); its ablation resulted in necrosis of stem cells and CSCs, which further triggers a...
2.
Higuchi T, Han Q, Sugisawa N, Yamamoto J, Yamamoto N, Hayashi K, et al.
Cancer Genomics Proteomics
. 2021 Feb;
18(2):113-120.
PMID: 33608308
Background/aim: Cancers are selectively sensitive to methionine (MET) restriction (MR) due to their addiction to MET which is overused for elevated methylation reactions. MET addiction of cancer was discovered by...
3.
Zhang Z, Hu K, Miyake K, Kiyuna T, Oshiro H, Wangsiricharoen S, et al.
Sci Rep
. 2020 Nov;
10(1):20105.
PMID: 33208807
Liver metastasis is a recalcitrant disease that usually leads to death of the patient. The present study established a unique patient-derived orthotopic xenograft (PDOX) nude mouse model of a highly...
4.
Tashiro Y, Nishino H, Higuchi T, Sugisawa N, Fukuda Y, Yamamoto J, et al.
Sci Rep
. 2020 Oct;
10(1):18565.
PMID: 33122687
Ischemia reperfusion injury (IRI) during liver-metastasis resection for treatment of colon cancer may increase the risk of further metastasis. Peroxisome proliferator-activated receptor-γ (PPARγ) activation has been observed to exert a...
5.
Yamamoto J, Miyake K, Han Q, Tan Y, Inubushi S, Sugisawa N, et al.
Cancer Lett
. 2020 Aug;
492:174-184.
PMID: 32739322
Methionine addiction is a fundamental and general hallmark of cancer. Gene expression analysis showed that methionine restriction (MR) of methionine-addicted cancer cells increases TNF-related apoptosis-induced ligand receptor-2 (TRAIL-R2) expression. Here,...
6.
Higuchi T, Sugisawa N, Park J, Sun Y, Zhu G, Yamamoto N, et al.
Transl Oncol
. 2020 Jul;
13(10):100826.
PMID: 32659740
Bone is one of the most frequent metastatic sites in non-small cell lung cancer (NSCLC). Osimertinib, with and without bevacizumab (BV), has been investigated on advanced NSCLC patients. However, the...
7.
Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Higuchi T, Yamamoto N, et al.
Cancer Genomics Proteomics
. 2020 Jun;
17(4):351-358.
PMID: 32576580
Background/aim: Dedifferentiated liposarcoma (DDLPS) is recalcitrant type of sarcoma. DDLPS has a low survival rate with high recurrence and metastasis. In the present study, we evaluated the efficacy of several...
8.
Igarashi K, Kawaguchi K, Zhao M, Han Q, Tan Y, Kiyuna T, et al.
Anticancer Res
. 2020 May;
40(5):2515-2523.
PMID: 32366396
Background/aim: Dedifferentiated liposarcoma (DDLPS) is associated with a poor survival rate even with multi-modality treatment. In the present study, we evaluated the efficacy of recombinant methioninase (rMETase) combined with tumor-targeting...
9.
Yamamoto J, Murata T, Tashiro Y, Higuchi T, Sugisawa N, Nishino H, et al.
Anticancer Res
. 2020 May;
40(5):2509-2514.
PMID: 32366395
Background/aim: Matrix-producing breast carcinoma (MPBC) is a rare and usually aggressive triple-negative breast cancer (TNBC). In this study, we determined drug sensitivity for a triple-negative MPBC, without BRCA mutations, in...
10.
Lim H, Yamamoto J, Inubushi S, Nishino H, Tashiro Y, Sugisawa N, et al.
Anticancer Res
. 2020 May;
40(5):2481-2485.
PMID: 32366392
Background/aim: In the present study, the breast cancer patient-derived orthotopic xenograft (PDOX) model was used to identify an effective drug for a highly aggressive triple negative breast cancer (TNBC). Materials...