Norihiko Sugisawa
Overview
Explore the profile of Norihiko Sugisawa including associated specialties, affiliations and a list of published articles.
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73
Citations
646
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Recent Articles
1.
Morikawa T, Wakui Y, Hasegawa Y, Sugisawa N, Kimura S, Hirashima T, et al.
Asian J Endosc Surg
. 2025 Jan;
18(1):e13415.
PMID: 39746373
Constitutional indocyanine green (ICG) excretion defect (CIED) is a rare clinical condition characterized by markedly delayed ICG disappearance with other normal liver function tests. Here, we report a case of...
2.
Soeta T, Sugisawa N, Yamamura A, Tanaka N, Imoto H, Tsuchiya T, et al.
Anticancer Res
. 2024 Dec;
44(12):5231-5240.
PMID: 39626906
Background/aim: MRTX1719 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor that targets the PRMT5-5'-Methylthioadenosine (MTA) complex called MTA-cooperative PRMT5 inhibitor. MRTX1719 acts specifically on methylthioadenosine phosphorylase (MTAP)-deficient cancer cells;...
3.
Miyake M, Miyake K, Han Q, Igarashi K, Kawaguchi K, Barangi M, et al.
Biochem Biophys Res Commun
. 2022 Dec;
643:48-54.
PMID: 36586158
Gastric cancer is highly malignant and recalcitrant to first line chemotherapies that include 5-fluorouracil (5-FU). Cancer cells are addicted to methionine for their proliferation and survival. Methionine addiction of cancer...
4.
Okamoto S, Miyano K, Choshi T, Sugisawa N, Nishiyama T, Kotouge R, et al.
Biomed Pharmacother
. 2022 Oct;
155:113733.
PMID: 36271542
Pancreatic cancer is recalcitrant to treatment as it is highly metastatic and rapidly progressive. While observing the behavior of human pancreatic BxPC-3 cells using an optical assay device called TAXIScan,...
5.
Hamada K, Kubota Y, Aoki Y, Sugisawa N, Yamamoto J, Tashiro Y, et al.
In Vivo
. 2022 Jun;
36(4):1643-1646.
PMID: 35738603
Background/aim: Obesity is a major risk factor for colorectal cancer. The MC38 mouse colon-cancer cell line is a versatile syngeneic model of colon cancer in C57BL/6 mice. In the present...
6.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, et al.
iScience
. 2022 Apr;
25(4):104162.
PMID: 35434545
Methionine addiction, found in all types of cancer investigated, is because of the overuse of methionine by cancer cells for excess transmethylation reactions. In the present study, we compared the...
7.
Sugisawa N, Miyake K, Higuchi T, Oshiro H, Park J, Kawaguchi K, et al.
Anticancer Res
. 2022 Jan;
42(2):739-743.
PMID: 35093872
Background/aim: Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) model. An important goal of PDOX-model development is facile visualization of metastasis in live mice. In the present report we evaluated...
8.
Kawana T, Imoto H, Tanaka N, Aoki T, Yamamura A, Tsuchiya T, et al.
Gan To Kagaku Ryoho
. 2022 Jan;
48(13):1749-1751.
PMID: 35046318
A 54-year-old woman was presented with the intraabdominal mass to our hospital. Abdominal CT showed 22 cm tumor of the stomach with invasion to the pancreas and the spleen. Upper...
9.
Kokubo S, Ohnuma S, Murakami M, Kikuchi H, Funayama S, Suzuki H, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830383
The ATP-binding cassette subfamily G member 2 (ABCG2) transporter is involved in the development of multidrug resistance in cancer patients. Many inhibitors of ABCG2 have been reported to enhance the...
10.
Hamada K, Aoki Y, Yamamoto J, Hozumi C, Zhao M, Murata T, et al.
In Vivo
. 2021 Oct;
35(6):3067-3071.
PMID: 34697138
Background/aim: Triple-negative matrix-producing breast carcinoma (MPBC) is rare, recalcitrant, and highly aggressive. The present study aimed to determine the efficacy of tumor-targeting leucine-arginine auxotroph Salmonella typhimurium (S. typhimurium) A1-R on...