Shozeb Haider
Overview
Explore the profile of Shozeb Haider including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
2824
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Recent Articles
11.
Zhu Y, Gu J, Zhao Z, Chan A, Mojica M, Hujer A, et al.
J Chem Inf Model
. 2024 Apr;
64(9):3706-3717.
PMID: 38687957
L2 β-lactamases, serine-based class A β-lactamases expressed by , play a pivotal role in antimicrobial resistance (AMR). However, limited studies have been conducted on these important enzymes. To understand the...
12.
Alanazi A, Parkinson G, Haider S
Biochemistry
. 2024 Mar;
63(7):827-842.
PMID: 38481135
Telomeres are specialized structures, found at the ends of linear chromosomes in eukaryotic cells, that play a crucial role in maintaining the stability and integrity of genomes. They are composed...
13.
Chen S, Mack A, Hujer A, Bethel C, Bonomo R, Haider S
bioRxiv
. 2024 Feb;
PMID: 38370743
The expression of antibiotic-inactivating enzymes, such as -derived cephalosporinase-3 (PDC-3), is a major mechanism of intrinsic resistance in bacteria. To explore the relationships between structural dynamics and altered substrate specificity...
14.
Ahmed A, Chen S, Roman-Escorza M, Angell R, Oxenford S, McConville M, et al.
Sci Rep
. 2024 Feb;
14(1):3447.
PMID: 38342953
The tetrasubstituted naphthalene diimide compound QN-302 binds to G-quadruplex (G4) DNA structures. It shows high potency in pancreatic ductal adenocarcinoma (PDAC) cells and inhibits the transcription of cancer-related genes in...
15.
Parwana D, Gu J, Chen S, Bethel C, Marshall E, Hujer A, et al.
Angew Chem Int Ed Engl
. 2024 Jan;
63(12):e202317315.
PMID: 38227422
The amino acid substitutions in Klebsiella pneumoniae carbapenemase 2 (KPC-2) that have arisen in the clinic are observed to lead to the development of resistance to ceftazidime-avibactam, a preferred treatment...
16.
Singh A, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, et al.
Brain
. 2023 Dec;
147(4):1553-1570.
PMID: 38128548
Hydrocephalus, characterized by cerebral ventriculomegaly, is the most common disorder requiring brain surgery in children. Recent studies have implicated SMARCC1, a component of the BRG1-associated factor (BAF) chromatin remodelling complex,...
17.
Wang H, Rizvi S, Dong D, Lou J, Wang Q, Sopipong W, et al.
Elife
. 2023 Dec;
12.
PMID: 38127066
The coronavirus SARS-CoV-2 protects its RNA from being recognized by host immune responses by methylation of its 5' end, also known as capping. This process is carried out by two...
18.
Mack A, Kumar V, Taracila M, Mojica M, OShea M, Schinabeck W, et al.
Antimicrob Agents Chemother
. 2023 Oct;
67(11):e0079123.
PMID: 37850746
A wide variety of clinically observed single amino acid substitutions in the Ω-loop region have been associated with increased minimum inhibitory concentrations and resistance to ceftazidime (CAZ) and ceftolozane (TOL)...
19.
Qi S, Kumar A, Chen S, Zhou S, Parihar M, Villalobos C, et al.
Res Sq
. 2023 Aug;
PMID: 37609305
The nuclear METTL3-METTL14 transfers a methyl group from SAM to convert the of adenosine (A) in RNA to mA and in ssDNA to 6mA. mA marks are prevalent in eukaryotic...
20.
Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease
Pinard A, Ye W, Fraser S, Rosenfeld J, Pichurin P, Hickey S, et al.
Brain
. 2023 May;
146(9):3616-3623.
PMID: 37253099
Moyamoya disease, a cerebrovascular disease leading to strokes in children and young adults, is characterized by progressive occlusion of the distal internal carotid arteries and the formation of collateral vessels....