Shobha Gopalakrishnan
Overview
Explore the profile of Shobha Gopalakrishnan including associated specialties, affiliations and a list of published articles.
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10
Citations
149
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Recent Articles
1.
Clemow D, Wagner B, Marshallsay C, Benau D, LHeureux D, Brown D, et al.
Ther Innov Regul Sci
. 2018 May;
52(1):78-88.
PMID: 29714614
This article provides Section 2 of the 2017 Edition 2 Medical Writing Competency Model that describes the knowledge, skills, abilities, and behaviors that professional medical writers need in order to...
2.
Clemow D, Wagner B, Marshallsay C, Benau D, LHeureux D, Brown D, et al.
Ther Innov Regul Sci
. 2018 May;
52(1):70-77.
PMID: 29714611
This article provides Section 1 of the 2017 Edition 2 Medical Writing Competency Model that describes the core work functions and associated tasks and activities related to professional medical writing...
3.
Garner R, Gopalakrishnan S, McCauley J, Bednar R, Gaul S, Mosser S, et al.
Pharmacol Res Perspect
. 2016 Mar;
3(6):e00198.
PMID: 27022470
The preclinical pharmacodynamic and pharmacokinetic properties of 4-methylbenzyl (3S, 4R)-3-fluoro-4-[(Pyrimidin-2-ylamino) methyl] piperidine-1-carboxylate (CERC-301), an orally bioavailable selective N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) antagonist, were characterized to develop a translational...
4.
Gopalakrishnan S, Tripathi A, Tamiz A, Alkan S, Pandey N
Peptides
. 2012 Mar;
35(1):95-101.
PMID: 22401910
Tight junctions (TJ) control paracellular permeability and apical-basolateral polarity of epithelial cells. Dysregulated permeability is associated with pathological conditions, such as celiac disease and inflammatory bowel disease. TJ formation is...
5.
Gopalakrishnan S, Durai M, Kitchens K, Tamiz A, Somerville R, Ginski M, et al.
Peptides
. 2012 Mar;
35(1):86-94.
PMID: 22401908
Tight junctions (TJs) control paracellular permeability and apical-basolateral polarity of epithelial cells, and can be regulated by exogenous and endogenous stimuli. Dysregulated permeability is associated with pathological conditions, such as...
6.
Gopalakrishnan S, Pandey N, Tamiz A, Vere J, Carrasco R, Somerville R, et al.
Int J Pharm
. 2008 Oct;
365(1-2):121-30.
PMID: 18832018
Tight junctions (TJs) are intercellular structures that control paracellular permeability and epithelial polarity. It is now accepted that TJs are highly dynamic structures that are regulated in response to exogenous...
7.
Gopalakrishnan S, Hallett M, Atkinson S, Marrs J
Am J Physiol Cell Physiol
. 2006 Aug;
292(3):C1094-102.
PMID: 16928777
Renal ischemia and in vitro ATP depletion result in disruption of the epithelial tight junction barrier, which is accompanied by breakdown of plasma membrane polarity. Tight junction formation is regulated...
8.
Gopalakrishnan S, Dunn K, Marrs J
Methods
. 2003 Jun;
30(3):218-27.
PMID: 12798136
Cadherin adhesion molecules function in numerous cell biological processes that influence embryo development, normal cell physiology, and pathophysiology of many disease processes. Cadherins nucleate the assembly of the adherens junction,...
9.
Gopalakrishnan S, Hallett M, Atkinson S, Marrs J
Am J Physiol Cell Physiol
. 2003 Jun;
285(1):C102-11.
PMID: 12777255
Several signaling pathways that regulate tight junction and adherens junction assembly are being characterized. Calpeptin activates stress fiber assembly in fibroblasts by inhibiting SH2-containing phosphatase-2 (SHP-2), thereby activating Rho-GTPase signaling....
10.
Gopalakrishnan S, Dunn K, Marrs J
Am J Physiol Cell Physiol
. 2002 Jun;
283(1):C261-72.
PMID: 12055095
Rho family GTPase signaling regulates actin cytoskeleton and junctional complex assembly. Our previous work showed that RhoA signaling protects tight junctions from damage during ATP depletion. Here, we examined whether...