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Shivani C Kharod

Explore the profile of Shivani C Kharod including associated specialties, affiliations and a list of published articles. Areas
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Citations 77
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Recent Articles
1.
Kharod S, Hwang D, Choi H, Yoon K, Castillo P, Singer R, et al.
bioRxiv . 2023 Oct; PMID: 37781583
Teaser: The phosphorylation-state of S499 on FMRP can change FMRP granule structure and function to facilitate processive transport or local protein synthesis.
2.
Kharod S, Monday H, Yoon Y, Castillo P
STAR Protoc . 2023 Feb; 4(1):101986. PMID: 36853723
Presynaptic boutons in the mammalian brain are typically small and difficult to manipulate and study. Here, we present a protocol applying HaloTag self-labeling technology to detect de novo local protein...
3.
Monday H, Kharod S, Yoon Y, Singer R, Castillo P
Neuron . 2022 Jun; 110(16):2588-2606.e6. PMID: 35728596
Learning and memory rely on long-lasting, synapse-specific modifications. Although postsynaptic forms of plasticity typically require local protein synthesis, whether and how local protein synthesis contributes to presynaptic changes remain unclear....
4.
Kharod S, Hwang D, Das S, Yoon Y
Front Cell Dev Biol . 2021 Jun; 9:663367. PMID: 34178987
Neurons exhibit spatial compartmentalization of gene expression where localization of messenger RNAs (mRNAs) to distal processes allows for site-specific distribution of proteins through local translation. Recently, there have been reports...
5.
Kharod S, Kang S, Kadam S
Front Neurosci . 2019 May; 13:310. PMID: 31068771
Bumetanide (BTN or BUM) is a FDA-approved potent loop diuretic (LD) that acts by antagonizing sodium-potassium-chloride (Na-K-Cl) cotransporters, NKCC1 (SLc12a2) and NKCC2. While NKCC1 is expressed both in the CNS...
6.
Kharod S, Carter B, Kadam S
Dev Neurobiol . 2018 Aug; 78(11):1117-1130. PMID: 30136373
Neonatal seizures are harmful to the developing brain and are associated with mortality and long-term neurological comorbidities. Hypoxic-ischemic encephalopathy (HIE) seizures represent a significant proportion of such seizures. Phenobarbital (PB)...