Pablo E Castillo
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Explore the profile of Pablo E Castillo including associated specialties, affiliations and a list of published articles.
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102
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6189
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Recent Articles
1.
Garat J, Di Paolo A, Eastman G, Castillo P, Sotelo-Silveira J
Neuroscience
. 2025 Jan;
567:195-208.
PMID: 39755230
Local protein synthesis (LPS) in axons is now recognized as a physiological process, participating both in the maintenance of axonal function and diverse plastic phenomena. In the last decades of...
2.
Rojas R, Grinan-Ferre C, Castellanos A, Griego E, Martinez M, Navarro-Lopez J, et al.
bioRxiv
. 2024 Aug;
PMID: 39091837
The ketogenic diet, characterized by high fat and low carbohydrates, has gained popularity not only as a strategy for managing body weight but also for its efficacy in delaying cognitive...
3.
Nasrallah K, Berthoux C, Hashimotodani Y, Chavez A, Gulfo M, Lujan R, et al.
Cell Rep
. 2024 Jun;
43(7):114382.
PMID: 38905101
Retrograde signaling at the synapse is a fundamental way by which neurons communicate and neuronal circuit function is fine-tuned upon activity. While long-term changes in neurotransmitter release commonly rely on...
4.
Ward C, Nasrallah K, Tran D, Sabri E, Vazquez A, Sjulson L, et al.
Biol Psychiatry
. 2024 Jun;
96(10):804-814.
PMID: 38848814
Background: MEF2C is strongly linked to various neurodevelopmental disorders including autism, intellectual disability, schizophrenia, and attention-deficit/hyperactivity disorder. Mice that constitutively lack 1 copy of Mef2c or selectively lack both copies...
5.
Ward C, Nasrallah K, Tran D, Sabri E, Vazquez A, Sjulson L, et al.
bioRxiv
. 2024 May;
PMID: 38746148
is strongly linked to various neurodevelopmental disorders (NDDs) including autism, intellectual disability, schizophrenia, and attention-deficit/hyperactivity. Mice constitutively lacking one copy of , or selectively lacking both copies of in cortical...
6.
Castillo P, Desarmenien M, Siegelbaum S
Neuron
. 2024 May;
112(9):1387-1389.
PMID: 38697022
No abstract available.
7.
Rangel-Sandoval C, Soula M, Li W, Castillo P, Hunt D
iScience
. 2024 Apr;
27(5):109681.
PMID: 38680664
Pannexins are large-pore ion channels expressed throughout the mammalian brain that participate in various neuropathologies; however, their physiological roles remain obscure. Here, we report that pannexin1 channels (Panx1) can be...
8.
Catala-Solsona J, Lutzu S, Lituma P, Fabregas-Ordonez C, Siedlecki D, Gimenez-Llort L, et al.
bioRxiv
. 2024 Feb;
PMID: 38328087
Alzheimer's disease AD is associated with disruptions in neuronal communication, especially in brain regions crucial for learning and memory, such as the hippocampus. The amyloid hypothesis suggests that the accumulation...
9.
Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function
Gulfo M, Lebowitz J, Ramos C, Hwang D, Nasrallah K, Castillo P
Proc Natl Acad Sci U S A
. 2023 Dec;
120(50):e2307509120.
PMID: 38064513
Hilar mossy cells (MCs) are principal excitatory neurons of the dentate gyrus (DG) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety...
10.
Castillo P, Jung H, Klann E, Riccio A
J Neurosci
. 2023 Nov;
43(45):7483-7488.
PMID: 37940588
Local protein synthesis in mature brain axons regulates the structure and function of presynaptic boutons by adjusting the presynaptic proteome to local demands. This crucial mechanism underlies experience-dependent modifications of...