Shitong Chen
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Explore the profile of Shitong Chen including associated specialties, affiliations and a list of published articles.
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11
Citations
46
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Recent Articles
1.
Chen S, Zhang D, Du Y, Shi J, Gu S, Zhou X, et al.
Cell Death Dis
. 2024 Dec;
15(12):924.
PMID: 39706834
Chemoresistance poses a significant clinical challenge in the treatment of gastric cancer (GC), while its underlying molecular mechanisms are still not fully understood. Post-translational protein modification and abnormal activation of...
2.
Ding Y, Zhu Z, Zhang K, Chen S, Han W, Ma C, et al.
Sci Rep
. 2024 Nov;
14(1):28729.
PMID: 39567653
To address the need for rapid repair and emergency support of traffic capacity in damaged tunnels, this study proposed a new structure combining arches assembled from steel plates and shotcrete...
3.
Ma G, Zang X, Chen S, Zhi M, Huang X
Sci Rep
. 2024 Sep;
14(1):20717.
PMID: 39237633
To quickly assess slope stability based on field displacement monitoring data, this paper constructs a hybrid optimization model that predicts surface displacement during tunnel excavation in base-overburden slopes. The model...
4.
Wang Y, Wang P, Wang Q, Chen S, Wang X, Zhong X, et al.
Biochem Pharmacol
. 2024 Jan;
220:116016.
PMID: 38176619
Cytochrome P450 3A4 (CYP3A4) is the most important and abundant drug-metabolizing enzyme in the human liver. Inter-individual differences in the expression and activity of CYP3A4 affect clinical and precision medicine....
5.
Wang F, Chen S, Peng S, Zhou X, Tang H, Liang H, et al.
Genes Dis
. 2023 Aug;
10(6):2622-2638.
PMID: 37554218
Protein arginine methyltransferase 1 (PRMT1), a type I PRMT, is overexpressed in gastric cancer (GC) cells. To elucidate the function of PRMT1 in GC, PRMT1 expression in HGC-27 and MKN-45 ...
6.
Shi C, Yan L, Gao J, Chen S, Zhang L
Br J Clin Pharmacol
. 2022 Apr;
88(10):4505-4514.
PMID: 35487881
Aims: To investigate the effects of ABCB1 DNA methylation in donors on individual differences in tacrolimus blood concentrations following liver transplantation. Methods: Twenty-three donor liver samples carrying the CYP3A5*3/*3 genotype...
7.
Wang F, Zhang J, Tang H, Pang Y, Ke X, Peng W, et al.
Oncogene
. 2021 Nov;
41(2):246-259.
PMID: 34725461
Gastric cancer (GC) has the fifth highest incidence globally, but its molecular mechanisms are not well understood. Here, we report that coactivator-associated arginine methyltransferase 1 (CARM1) is specifically highly expressed...
8.
Wang P, Chen S, Wang Y, Wang X, Yan L, Yang K, et al.
Drug Metab Dispos
. 2021 Mar;
49(5):361-368.
PMID: 33674270
The maintenance of homeostasis of cytochromes P450 enzymes (P450s) under both physiologic and xenobiotic exposure conditions is ensured by the action of positive and negative regulators. In the current study,...
9.
Wang X, Wei L, Yang J, Wang Y, Chen S, Yang K, et al.
Clin Exp Pharmacol Physiol
. 2020 Oct;
48(2):250-259.
PMID: 33048369
The expression and activity of CYP3A4 vary among individuals. With the development of epigenetics, it is now possible to elucidate interindividual differences in drug-metabolizing enzymes. Here, we aimed to explore...
10.
Liu K, Chen S, Chen F, Zhu X
Polymers (Basel)
. 2020 Mar;
12(3).
PMID: 32182735
Dielectric elastomer actuators (DEAs) are able to undergo large deformation in response to external electric stimuli and have been widely used to drive soft robotic systems, due to their advantageous...