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Shirine Benhenda

Explore the profile of Shirine Benhenda including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 805
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Recent Articles
1.
Bercier P, Wang Q, Zang N, Zhang J, Yang C, Maimaitiyiming Y, et al.
Cancer Discov . 2023 Sep; 13(12):2548-2565. PMID: 37655965
Significance: Arsenic curative effects in APL rely on PML targeting. We report a PML B-box-2 structure that drives trimer assembly, positioning a cysteine trio to form an arsenic-binding pocket, which...
2.
Wu H, Rerolle D, Berthier C, Hleihel R, Sakamoto T, Quentin S, et al.
Cancer Discov . 2021 Jul; 11(12):3198-3213. PMID: 34301789
Significance: ActD induces complete remissions in NPM1-mutant AMLs. We found that NPM1c affects mitochondrial biogenesis and PML NBs. ActD targets mitochondria, yielding ROS which enforce PML NB biogenesis and restore...
3.
Ducroux A, Benhenda S, Riviere L, John Semmes O, Benkirane M, Neuveut C
PLoS Pathog . 2020 Dec; 16(12):e1009135. PMID: 33306747
[This corrects the article DOI: 10.1371/journal.ppat.1004343.].
4.
Wang P, Benhenda S, Wu H, Lallemand-Breitenbach V, Zhen T, Jollivet F, et al.
Nat Commun . 2018 May; 9(1):1841. PMID: 29728567
In the originally published version of this Article, the authors Sai-Juan Chen and Zhu Chen were incorrectly listed as being affiliated with 'University Paris Diderot, Sorbonne Paris Cité, INSERM U944,...
5.
Wang P, Benhenda S, Wu H, Lallemand-Breitenbach V, Zhen T, Jollivet F, et al.
Nat Commun . 2018 Mar; 9(1):1277. PMID: 29599493
ProMyelocyticLeukemia nuclear bodies (PML NBs) are stress-regulated domains directly implicated in acute promyelocytic leukemia eradication. Most TRIM family members bind ubiquitin E2s and many acquire ligase activity upon RING dimerization....
6.
Poirot B, Doucet L, Benhenda S, Champ J, Meignin V, Lehmann-Che J
J Thorac Oncol . 2017 Aug; 12(10):1582-1587. PMID: 28779874
Introduction: Targeted therapies such as tyrosine kinase inhibitors (TKIs) have dramatically improved the treatment of lung adenocarcinoma, and detection of activating mutations of genes such as EGFR or anaplastic lymphoma...
7.
Ducroux A, Benhenda S, Riviere L, John Semmes O, Benkirane M, Neuveut C
PLoS Pathog . 2014 Sep; 10(9):e1004343. PMID: 25211330
Hepatitis B virus infection (HBV) is a major risk factor for the development of hepatocellular carcinoma. HBV replicates from a covalently closed circular DNA (cccDNA) that remains as an episome...
8.
Sahin U, Ferhi O, Jeanne M, Benhenda S, Berthier C, Jollivet F, et al.
J Cell Biol . 2014 Mar; 204(6):931-45. PMID: 24637324
The promyelocytic leukemia (PML) protein organizes PML nuclear bodies (NBs), which are stress-responsive domains where many partner proteins accumulate. Here, we clarify the basis for NB formation and identify stress-induced...
9.
Benhenda S, Ducroux A, Riviere L, Sobhian B, Ward M, Dion S, et al.
J Virol . 2013 Feb; 87(8):4360-71. PMID: 23388725
The hepatitis B virus X protein (HBx) is essential for virus replication and has been implicated in the development of liver cancer. HBx is recruited to viral and cellular promoters...
10.
Cougot D, Allemand E, Riviere L, Benhenda S, Duroure K, Levillayer F, et al.
Sci Signal . 2012 Jan; 5(205):ra1. PMID: 22215732
The regulatory protein HBx is essential for hepatitis B virus (HBV) replication in vivo and for transcription of the episomal HBV genome. We previously reported that in infected cells HBx...