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Shireen Chikara

Explore the profile of Shireen Chikara including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 460
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Recent Articles
11.
Chikara S, Lindsey K, Dhillon H, Mamidi S, Kittilson J, Christofidou-Solomidou M, et al.
Nutr Cancer . 2017 Mar; 69(4):652-662. PMID: 28323486
Flaxseed is a rich source of the plant lignan secoisolariciresinol diglucoside (SDG), which is metabolized into mammalian lignans enterodiol (ED) and enterolactone (EL) in the digestive tract. The anticancer properties...
12.
Chikara S, Lindsey K, Borowicz P, Christofidou-Solomidou M, Reindl K
BMC Complement Altern Med . 2017 Jan; 17(1):30. PMID: 28068967
Background: Systemic toxicity of chemotherapeutic agents and the challenges associated with targeting metastatic tumors are limiting factors for current lung cancer therapeutic approaches. To address these issues, plant-derived bioactive components...
13.
Chikara S, Reindl K
Transl Lung Cancer Res . 2015 Mar; 2(6):449-51. PMID: 25806268
The Notch signal transduction pathway regulates cell fate decisions throughout embryonic development. The mechanisms through which Notch signaling maintains cellular integrity are well understood. However, Notch signaling is more complex...
14.
Dhillon H, Chikara S, Reindl K
Toxicol Rep . 2014 Dec; 1:309-318. PMID: 25530945
Pancreatic cancer is one of the most deadly cancers with a nearly 95% mortality rate. The poor response of pancreatic cancer to currently available therapies and the extremely low survival...
15.
Randhawa H, Chikara S, Gehring D, Yildirim T, Menon J, Reindl K
BMC Cancer . 2013 Jul; 13:321. PMID: 23815882
Background: Human mitochondrial peptide deformylase (PDF) has been proposed as a novel cancer therapeutic target. However, very little is known about its expression and regulation in human tissues. The purpose...
16.
McConnell M, Mamidi S, Lee R, Chikara S, Rossi M, Papa R, et al.
Theor Appl Genet . 2010 Jul; 121(6):1103-16. PMID: 20607211
Molecular linkage maps are an important tool for gene discovery and cloning, crop improvement, further genetic studies, studies on diversity and evolutionary history, and cross-species comparisons. Linkage maps differ in...
17.
McClean P, Mamidi S, McConnell M, Chikara S, Lee R
BMC Genomics . 2010 Mar; 11:184. PMID: 20298570
Background: Understanding syntentic relationship between two species is critical to assessing the potential for comparative genomic analysis. Common bean (Phaseolus vulgaris L.) and soybean (Glycine max L.), the two most...