Shireen Chikara
Overview
Explore the profile of Shireen Chikara including associated specialties, affiliations and a list of published articles.
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16
Citations
460
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Recent Articles
1.
Tang X, Pesola G, Chen Q, Miller D, Nagy L, McMullen M, et al.
Alcohol Clin Exp Res (Hoboken)
. 2025 Feb;
PMID: 40016864
Background: Chronic alcohol drinking causes hepatic vitamin A (retinoids and derivatives) decreases, which correlate with the progression and severity of alcohol-associated liver disease (ALD). However, the effects of short-term ethanol...
2.
Singhal J, Chikara S, Horne D, Awasthi S, Salgia R, Singhal S
Carcinogenesis
. 2020 May;
42(1):48-57.
PMID: 32426802
Breast cancer (BC) remains one of the major causes of cancer deaths in women. Over half of all BCs carry genetic defects in the gene encoding p53, a powerful tumor...
3.
Singhal J, Chikara S, Horne D, Salgia R, Awasthi S, Singhal S
Cancer Lett
. 2019 Jan;
447:24-32.
PMID: 30684594
Breast tumor metastasis is a leading cause of cancer-related deaths worldwide. Breast cancer (BC) cells frequently metastasize to the lungs, where they pose a formidable therapeutic challenge. In the current...
4.
Nagaprashantha L, Singhal J, Chikara S, Gugiu G, Horne D, Awasthi S, et al.
J Proteomics
. 2018 Sep;
192:233-245.
PMID: 30248461
In spite of rapid advances in understanding of signaling networks associated with the incidence and therapeutic-sensitivity, breast cancer (BC) still remains the most commonly diagnosed and prevalent cancer in women....
5.
Singhal J, Chikara S, Horne D, Salgia R, Awasthi S, Singhal S
Mol Carcinog
. 2018 Aug;
57(12):1751-1762.
PMID: 30136444
Consumption of citrus-fruits is associated with reduced incidence of breast cancer (BC), the most common cancer diagnosed in women across the globe. In this study, we investigated the anticancer potential...
6.
Mohammad J, Dhillon H, Chikara S, Mamidi S, Sreedasyam A, Chittem K, et al.
Oncotarget
. 2018 Mar;
9(12):10457-10469.
PMID: 29535819
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers due to a late diagnosis and poor response to available treatments. There is a need to identify complementary treatment strategies...
7.
Chikara S, Nagaprashantha L, Singhal J, Horne D, Awasthi S, Singhal S
Cancer Lett
. 2017 Nov;
413:122-134.
PMID: 29113871
Several epidemiological observations have shown an inverse relation between consumption of plant-based foods, rich in phytochemicals, and incidence of cancer. Phytochemicals, secondary plant metabolites, via their antioxidant property play a...
8.
Singhal J, Nagaprashantha L, Chikara S, Awasthi S, Horne D, Singhal S
Oncotarget
. 2017 Nov;
8(43):75025-75037.
PMID: 29088842
Breast cancer is the most common cancer in women that is driven by cross-talk with hormonal and cellular signaling pathways. The natural phytochemicals, due to broad-spectrum anti-inflammatory and anti-cancerous properties,...
9.
Chikara S, Mamidi S, Sreedasyam A, Chittem K, Pietrofesa R, Zuppa A, et al.
Cancer Prev Res (Phila)
. 2017 Oct;
11(1):27-37.
PMID: 29074535
Flaxseed consumption is associated with reduced oxidative stress and inflammation in lung injury models and has shown anticancer effects for breast and prostate tissues. However, the chemopreventive potential of flaxseed...
10.
Nagaprashantha L, Adhikari R, Singhal J, Chikara S, Awasthi S, Horne D, et al.
Int J Cancer
. 2017 Oct;
142(4):658-670.
PMID: 28975625
Breast cancer (BC) prevention and therapy in the context of life-style risk factors and biological drivers is a major focus of developmental therapeutics in oncology. Obesity, alcohol, chronic estrogen signaling...