Shin-Ichi Yokota
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Explore the profile of Shin-Ichi Yokota including associated specialties, affiliations and a list of published articles.
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176
Citations
1846
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Recent Articles
1.
Shiraishi T, Katsuki R, Kumeta H, Sakata S, Yokota S
FEMS Microbiol Lett
. 2025 Jan;
372.
PMID: 39814573
Latilactobacillus curvatus, found in various fermented foods, is a promising probiotic with unique health benefits. Lipoteichoic acid (LTA) is a characteristic amphiphilic surface polymer of Gram-positive bacteria and exhibits immunomodulatory...
2.
Yamasaki-Yashiki S, Shiraishi T, Gyobu M, Sasaki H, Kunisawa J, Yokota S, et al.
Appl Environ Microbiol
. 2024 Sep;
90(10):e0119724.
PMID: 39240119
Importance: Some lactic acid bacteria activate the host intestinal immune system via toll-like receptor (TLR) 2. Lipoteichoic acid (LTA) is a TLR2 ligand; however, the moieties of LTA that determine...
3.
Shiraishi T, Yokota S
Methods Mol Biol
. 2024 Aug;
2851:39-60.
PMID: 39210170
Gram-positive bacteria, including lactic acid bacteria (LAB), possess lipoteichoic acid (LTA) on the cell surface. LTA is an amphiphilic molecule typically composed of hydrophilic glycerolphosphate polymer and hydrophobic anchor glycolipid...
4.
Sato T, Uemura K, Yasuda M, Maeda A, Minamoto T, Harada K, et al.
One Health
. 2024 Jul;
18:100715.
PMID: 39010959
Transmission of antimicrobial-resistant bacteria among humans, animals, and the environment is a growing concern worldwide. The distribution of an international high-risk fluoroquinolone-resistant clone, ST131, has been documented in clinical settings....
5.
Yamamoto K, Sato T, Hao A, Asao K, Kaguchi R, Kusaka S, et al.
Nat Commun
. 2024 Jun;
15(1):5085.
PMID: 38877016
MraY (phospho-N-acetylmuramoyl-pentapeptide-transferase) inhibitory natural products are attractive molecules as candidates for a new class of antibacterial agents to combat antimicrobial-resistant bacteria. Structural optimization of these natural products is required to...
6.
Shiraishi T, Matsuzaki C, Chiou T, Kumeta H, Kawada M, Yamamoto K, et al.
Int J Biol Macromol
. 2024 May;
271(Pt 1):132540.
PMID: 38782319
Lipoteichoic acid (LTA) in the gram-positive bacterial cell wall acts as an immunomodulatory factor in host cells. The chemical structures vary among bacterial species and strains, and may be related...
7.
Yamada N, Kamoshida G, Shiraishi T, Yamaguchi D, Matsuoka M, Yamauchi R, et al.
J Bacteriol
. 2024 Apr;
206(5):e0043523.
PMID: 38661375
Importance: Antimicrobial resistance (AMR) is a pressing global issue in human health. is notably high on the World Health Organization's list of bacteria for which new antimicrobial agents are urgently...
8.
Yamamoto S, Ogasawara N, Mitsuhashi Y, Takano K, Yokota S
Sci Rep
. 2024 Jan;
14(1):2354.
PMID: 38287119
The mechanism underlying the anti-inflammatory effect of macrolide antibiotics, such as clarithromycin (CAM), remains to be clarified. The CAM-binding proteins 4-nitrophenylphosphatase domain and non-neuronal synaptosomal associated protein 25 (SNAP25)-like protein...
9.
Hiyama Y, Yamamoto S, Sato T, Ogasawara N, Masumori N, Takahashi S, et al.
Microb Drug Resist
. 2024 Jan;
30(3):141-146.
PMID: 38215246
Multidrug-resistant is a serious concern worldwide. Resistance to β-lactam antibiotics occurs through mutations in penicillin-binding proteins (PBPs), acquisition of β-lactamases, and alteration of antibiotic penetration. Mosaic structures of , which...
10.
Konno A, Okubo T, Enoeda Y, Uno T, Sato T, Yokota S, et al.
PLoS One
. 2023 Sep;
18(9):e0291765.
PMID: 37729194
Healthcare-associated infections have become a major health issue worldwide. One route of transmission of pathogenic bacteria is through contact with "high-touch" dry surfaces, such as handrails. Regular cleaning of surfaces...