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Shilpa Choudhary

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Articles 29
Citations 373
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Recent Articles
11.
Choudhary S, Goetjen A, Estus T, Jacome-Galarza C, Aguila H, Lorenzo J, et al.
J Biol Chem . 2015 Dec; 291(8):3882-94. PMID: 26703472
Continuous parathyroid hormone (PTH) blocks its own osteogenic actions in marrow stromal cell cultures by inducing Cox2 and receptor activator of nuclear factor κB ligand (RANKL) in the osteoblastic lineage...
12.
Tyagi K, Gupta D, Saini E, Choudhary S, Jamwal A, Alam M, et al.
PLoS One . 2015 Sep; 10(9):e0138691. PMID: 26393350
Background: The monkey malaria parasite Plasmodium knowlesi also infect humans. There is a lack of information on the molecular mechanisms that take place between this simian parasite and its heterologous...
13.
Choudhary S, Canalis E, Estus T, Adams D, Pilbeam C
PLoS One . 2015 Mar; 10(3):e0120164. PMID: 25781979
We previously reported that the ability of continuously elevated PTH to stimulate osteoblastic differentiation in bone marrow stromal cell cultures was abrogated by an osteoclastic factor secreted in response to...
14.
Choudhary D, Hegde P, Voznesensky O, Choudhary S, Kopsiaftis S, Claffey K, et al.
Urol Oncol . 2015 Jan; 33(9):387.e17-27. PMID: 25618296
Introduction: L-Selectin (CD62L) is a vascular adhesion molecule constitutively expressed on leukocytes with a primary function of directing leukocyte migration and homing of lymphocytes to lymph nodes. In a gene...
15.
Choudhary S, Hegde P, Pruitt J, Sielecki T, Choudhary D, Scarpato K, et al.
Carcinogenesis . 2013 Jul; 34(12):2891-9. PMID: 23825153
Macrophage migratory inhibitory factor (MIF) is a proinflammatory cytokine shown to promote tumorigenesis. Using the N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) model of bladder cancer, we previously showed that MIF knockout mice display decreased...
16.
Choudhary S, Blackwell K, Voznesensky O, Roy A, Pilbeam C
Bone . 2013 May; 56(1):31-41. PMID: 23639875
Intermittent PTH is the major anabolic therapy for osteoporosis while continuous PTH causes bone loss. PTH acts on the osteoblast (OB) lineage to regulate bone resorption and formation. PTH also...
17.
Xu M, Choudhary S, Voznesensky O, Gao Q, Adams D, Diaz-Doran V, et al.
Bone . 2010 May; 47(2):341-52. PMID: 20471507
Cyclooxygenase-2 (COX-2) knockout (KO) mice in inbred strains can have renal dysfunction with secondary hyperparathyroidism (HPTH), making direct effects of COX-2 KO on bone difficult to assess. COX-2 KO mice...
18.
Blackwell K, Hortschansky P, Sanovic S, Choudhary S, Raisz L, Pilbeam C
Prostaglandins Other Lipid Mediat . 2009 Sep; 90(3-4):76-80. PMID: 19744575
Bone morphogenetic protein 2 (BMP-2) is used clinically to stimulate bone formation and accelerate fracture repair. Adding prostaglandin (PG) E(2) or PGE(2) receptor agonists to BMP-2 has been proposed to...
19.
Gao Q, Xu M, Alander C, Choudhary S, Pilbeam C, Raisz L
Prostaglandins Other Lipid Mediat . 2009 May; 89(1-2):20-5. PMID: 19464663
We have examined the effects of varying doses, schedules and routes of administration of prostaglandin E(2) (PGE(2)) on bone in mice. Male C57BL/6 mice treated with a high dose of...
20.
Choudhary S, Huang H, Raisz L, Pilbeam C
Biochem Biophys Res Commun . 2008 May; 372(4):536-41. PMID: 18501188
PTH is a potent bone anabolic agent in vivo but anabolic effects on osteoblast differentiation in vitro are difficult to demonstrate. This study examined the role of cyclooxygenase (COX)-2 and...