Carol C Pilbeam
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Explore the profile of Carol C Pilbeam including associated specialties, affiliations and a list of published articles.
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28
Citations
610
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Recent Articles
1.
Woolbright B, Pilbeam C, Taylor 3rd J
Prostaglandins Other Lipid Mediat
. 2020 Jan;
148:106409.
PMID: 31931078
Bladder cancer (BCa) is a common solid tumor marked by high rates of recurrence, especially in non-muscle invasive disease. Prostaglandin E (PGE) is a ubiquitously present lipid mediator responsible for...
2.
Woolbright B, Choudhary D, Mikhalyuk A, Trammel C, Shanmugam S, Abbott E, et al.
Mol Cancer Ther
. 2018 Jun;
17(9):2004-2012.
PMID: 29907593
Advanced bladder cancer remains a major source of mortality, with poor treatment options. Cisplatin-based chemotherapy is the standard treatment, however many patients are or become resistant. One potential cause of...
3.
Choudhary D, Clement J, Choudhary S, Voznesensky O, Pilbeam C, Woolbright B, et al.
Urol Oncol
. 2017 Oct;
36(3):93.e13-93.e21.
PMID: 29079132
Purpose: SATB1, a global genome organizer, has been shown to play a role in the development and progression of some solid tumors, but its role in bladder cancer is undetermined....
4.
Roy A, Yin T, Choudhary S, Rodionov V, Pilbeam C, Wu Y
Nat Commun
. 2017 Jun;
8:15831.
PMID: 28635959
During bone remodelling, osteoclasts induce chemotaxis of osteoblasts and yet maintain spatial segregation. We show that osteoclasts express the repulsive guidance factor Semaphorin 4D and induce contact inhibition of locomotion...
5.
Estus T, Choudhary S, Pilbeam C
Bone
. 2016 Feb;
85:123-30.
PMID: 26851123
Bone marrow macrophages (BMMs), in the presence of cyclooxygenase-2 (Cox2) produced PGE2, secrete an inhibitory factor in response to Rankl that blocks PTH-stimulated osteoblastic differentiation. This study was to determine...
6.
Choudhary D, Hegde P, Voznesensky O, Choudhary S, Kopsiaftis S, Claffey K, et al.
Urol Oncol
. 2015 Jan;
33(9):387.e17-27.
PMID: 25618296
Introduction: L-Selectin (CD62L) is a vascular adhesion molecule constitutively expressed on leukocytes with a primary function of directing leukocyte migration and homing of lymphocytes to lymph nodes. In a gene...
7.
Lalla R, Choquette L, Curley K, Dowsett R, Feinn R, Hegde U, et al.
Oral Oncol
. 2014 Aug;
50(11):1098-103.
PMID: 25151488
Objectives: Oral mucositis (OM) is a painful complication of radiation therapy (RT) for head and neck cancer (H&NC). OM can compromise nutrition, require opioid analgesics and hospitalization for pain control,...
8.
Choudhary S, Hegde P, Pruitt J, Sielecki T, Choudhary D, Scarpato K, et al.
Carcinogenesis
. 2013 Jul;
34(12):2891-9.
PMID: 23825153
Macrophage migratory inhibitory factor (MIF) is a proinflammatory cytokine shown to promote tumorigenesis. Using the N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) model of bladder cancer, we previously showed that MIF knockout mice display decreased...
9.
Xu M, Choudhary S, Voznesensky O, Gao Q, Adams D, Diaz-Doran V, et al.
Bone
. 2010 May;
47(2):341-52.
PMID: 20471507
Cyclooxygenase-2 (COX-2) knockout (KO) mice in inbred strains can have renal dysfunction with secondary hyperparathyroidism (HPTH), making direct effects of COX-2 KO on bone difficult to assess. COX-2 KO mice...
10.
Blackwell K, Raisz L, Pilbeam C
Trends Endocrinol Metab
. 2010 Jan;
21(5):294-301.
PMID: 20079660
Prostaglandins (PGs) are multifunctional regulators of bone metabolism that stimulate both bone resorption and formation. PGs have been implicated in bone resorption associated with inflammation and metastatic bone disease, and...