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Shigeo Wakabayashi

Explore the profile of Shigeo Wakabayashi including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 1187
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Recent Articles
1.
Morihara H, Yokoe S, Wakabayashi S, Takai S
FASEB Bioadv . 2024 Nov; 6(11):565-579. PMID: 39512841
Transmembrane protein 182 (TMEM182) is notably abundant in muscle and adipose tissue, but its role in the heart remains unknown. This study examined the contribution of TMEM182 in the differentiation...
2.
Tsuruoka K, Wakabayashi S, Morihara H, Matsunaga N, Fujisaka Y, Goto I, et al.
Int J Cardiol . 2020 May; 313:67-75. PMID: 32402518
Background: Although immune checkpoint inhibitors (ICIs) have made an immense breakthrough in cancer therapeutics, they can exert unique, immune-related adverse events. Among them, myocarditis is less frequent, but it is...
3.
Iwata Y, Wakabayashi S, Ito S, Kitakaze M
Lab Invest . 2020 Jan; 100(2):324-337. PMID: 31896817
Abnormal Ca handling is essential in the pathophysiology of degenerative muscle disorders, such as dilated cardiomyopathy (DCM) and muscular dystrophy (MD). Transient receptor potential cation channel, subfamily V, member 2...
4.
Iwata Y, Ito S, Wakabayashi S, Kitakaze M
Lab Invest . 2019 Dec; 100(2):207-217. PMID: 31857697
Heart transplantation is currently the only viable option available for the treatment of severe heart failure conditions such as dilated cardiomyopathy. Hence, novel drugs for treating such conditions need to...
5.
Wakabayashi S, Morihara H, Yokoe S, Nakagawa T, Moriwaki K, Tomoda K, et al.
J Biol Chem . 2019 Nov; 294(51):19577-19588. PMID: 31723030
Understanding the specific properties of human induced pluripotent stem cells (iPSCs) is important for quality control of iPSCs. Having incidentally discovered that overexpression of plasma membrane Na/H exchanger 1 (NHE1)...
6.
Masubuchi H, Ueno M, Maeno T, Yamaguchi K, Hara K, Sunaga H, et al.
BMC Pulm Med . 2019 Mar; 19(1):70. PMID: 30914062
Background: Defective phagocytosis in alveolar macrophages is associated with chronic obstructive pulmonary disease (COPD). Transient receptor potential cation channel subfamily V member 2 (TRPV2), a type of nonselective cation channel...
7.
Nakamura T, Nakao S, Wakabayashi S
Front Mol Neurosci . 2019 Mar; 12:56. PMID: 30886571
The EF-hand calcium (Ca)-binding protein, neuronal Ca sensor-1 (NCS-1/frequenin), is predominantly expressed in neuronal tissues and plays a crucial role in neuronal functions, including synaptic transmission and plasticity. NCS-1 has...
8.
Iwata Y, Katayama Y, Okuno Y, Wakabayashi S
Oncotarget . 2018 Mar; 9(18):14042-14057. PMID: 29581825
Transient receptor potential cation channel, subfamily V, member 2 (TRPV2) is a principal candidate for abnormal Ca-entry pathways, which is a potential target for therapy of muscular dystrophy and cardiomyopathy....
9.
Nakamura T, Nakao S, Nakajo Y, Takahashi J, Wakabayashi S, Yanamoto H
PLoS One . 2017 Jan; 12(1):e0170829. PMID: 28122057
Intracellular Ca2+ signaling regulates diverse functions of the nervous system. Many of these neuronal functions, including learning and memory, are regulated by neuronal calcium sensor-1 (NCS-1). However, the pathways by...
10.
Takamatsu G, Katagiri C, Tomoyuki T, Shimizu-Okabe C, Nakamura W, Nakamura-Higa M, et al.
Biochem Biophys Res Commun . 2016 Dec; 482(4):1327-1333. PMID: 27939885
Class I histone deacetylase (HDAC) inhibitors are believed to have positive effects on neurite outgrowth, synaptic plasticity, and neurogenesis in adult brain. However, the downstream molecular targets of class I...