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Sherri A Rennoll

Explore the profile of Sherri A Rennoll including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 338
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Recent Articles
1.
Voss O, Gillespie J, Lehman S, Rennoll S, Beier-Sexton M, Rahman M, et al.
mBio . 2020 Jun; 11(3). PMID: 32546622
To establish a habitable intracellular niche, various pathogenic bacteria secrete effectors that target intracellular trafficking and modulate phosphoinositide (PI) metabolism. Murine typhus, caused by the obligate intracellular bacterium , remains...
2.
Rennoll S, Rennoll-Bankert K, Guillotte M, Lehman S, Driscoll T, Beier-Sexton M, et al.
Infect Immun . 2017 Nov; 86(1). PMID: 29084898
species are obligate intracellular bacteria with both conserved and lineage-specific strategies for invading and surviving within eukaryotic cells. One variable component of biology involves arthropod vectors: for instance, typhus group...
3.
Driscoll T, Verhoeve V, Guillotte M, Lehman S, Rennoll S, Beier-Sexton M, et al.
mBio . 2017 Sep; 8(5). PMID: 28951473
Reductive genome evolution has purged many metabolic pathways from obligate intracellular (; ). While some aspects of host-dependent rickettsial metabolism have been characterized, the array of host-acquired metabolites and their...
4.
Eshelman M, Shah M, Raup-Konsavage W, Rennoll S, Yochum G
Biochem Biophys Res Commun . 2017 Apr; 487(3):716-722. PMID: 28450117
The T-cell factor/Lymphoid enhancer factor (TCF/LEF; hereafter TCF) family of transcription factors are critical regulators of colorectal cancer (CRC) cell growth. Of the four TCF family members, TCF7L1 functions predominantly...
5.
Rennoll S, Eshelman M, Raup-Konsavage W, Kawasawa Y, Yochum G
Cancers (Basel) . 2016 May; 8(5). PMID: 27223305
Mutations in components of the Wnt/β-catenin signaling pathway drive colorectal cancer (CRC) by deregulating expression of downstream target genes including the c-MYC proto-oncogene (MYC). The critical regulatory DNA enhancer elements...
6.
Shah M, Rennoll S, Raup-Konsavage W, Yochum G
Cell Cycle . 2015 Feb; 14(3):323-32. PMID: 25659031
Deregulated Wnt/β-catenin signaling promotes colorectal cancer (CRC) by activating expression of the c-MYC proto-oncogene (MYC). In the nucleus, the β-catenin transcriptional co-activator binds T-cell factor (TCF) transcription factors, and together...
7.
Rennoll S, Scott S, Yochum G
Biochem Biophys Res Commun . 2014 Mar; 446(4):1120-5. PMID: 24667606
Designer TALEs (dTALEs) are chimeric transcription factors that can be engineered to regulate gene expression in mammalian cells. Whether dTALEs can block gene transcription downstream of signal transduction cascades, however,...
8.
Rennoll S, Konsavage Jr W, Yochum G
Biochem Biophys Res Commun . 2013 Dec; 443(1):217-22. PMID: 24299953
The β-catenin transcriptional coactivator is the key mediator of the canonical Wnt signaling pathway. In the absence of Wnt, β-catenin associates with a cytosolic and multi-protein destruction complex where it...
9.
Konsavage Jr W, Kyler S, Rennoll S, Jin G, Yochum G
J Biol Chem . 2012 Feb; 287(15):11730-9. PMID: 22337891
Mutations in the Wnt/β-catenin pathway occur in most colorectal cancers (CRCs), and these mutations lead to increased nuclear accumulation of the β-catenin transcriptional co-activator. In the nucleus, β-catenin associates with...