Shengtao Xu
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Explore the profile of Shengtao Xu including associated specialties, affiliations and a list of published articles.
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Articles
118
Citations
943
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Recent Articles
11.
Zheng L, Zhang Y, Mei S, Xie T, Zou Y, Wang Y, et al.
J Med Chem
. 2024 Apr;
67(9):7130-7145.
PMID: 38630077
Multitarget medications represent an appealing therapy against the disease with multifactorial abnormalities─cancer. Therefore, simultaneously targeting son of sevenless 1 (SOS1) and epidermal growth factor receptor (EGFR), two aberrantly expressed proteins...
12.
Zhou Y, Yang L, Xu S, Li S, Zeng L, Shang H, et al.
Front Microbiol
. 2024 Apr;
15:1371336.
PMID: 38601934
Fusarium wilt of banana caused by f. sp. , Tropical Race 4 (TR4) is a soil-borne disease, and it is devastating. At present, the biological control using antagonistic microorganisms to...
13.
Zhang X, Xu S, Feng K, Li X, Yu P, Liu Q, et al.
Water Res
. 2024 Feb;
254:121351.
PMID: 38401287
The application of Fenton-like membrane reactors for water purification offers a promising solution to overcome technical challenges associated with catalyst recovery, reaction efficiency, and mass transfer typically encountered in heterogeneous...
14.
Zhu W, Wu H, He C, Zhu H, Yao H, Cao Y, et al.
RSC Med Chem
. 2024 Jan;
15(1):151-164.
PMID: 38283220
Herein, a series of novel β-elemene hybrids with different types of hydrogen sulfide (HS) donors was designed and synthesized for the first time. In addition, all compounds were tested for...
15.
Chen L, Gao T, Zhou P, Xia W, Yao H, Xu S, et al.
Bioorg Chem
. 2023 Dec;
143:107039.
PMID: 38134519
Autophagy is a ubiquitous pathological/physiological antioxidant cellular reaction in eukaryotic cells. Vacuolar protein sorting 34 (Vps34 or PIK3C3), which plays a crucial role in autophagy, has received much attention. As...
16.
Zheng L, Zou Y, Xie T, Wu X, Tan Y, Mei S, et al.
J Med Chem
. 2023 Dec;
66(23):16187-16200.
PMID: 38093696
Dual inhibition of tubulin and neuropilin-1 (NRP1) may become an effective method for cancer treatment by simultaneously killing tumor cells and inhibiting tumor angiogenesis. Herein, we identified dual tubulin/NRP1-targeting inhibitor...
17.
Tan Y, Hu H, Zhu W, Wang T, Gao T, Wang H, et al.
Eur J Med Chem
. 2023 Oct;
262:115881.
PMID: 37883897
A series of novel dihydroquinolin-4(1H)-one derivatives targeting colchicine binding site on tubulin were designed, synthesized and evaluated as anticancer agents. The most potent compound 6t showed remarkable antiproliferative activities against...
18.
Fan H, He P, Xu S, Li S, Wang Y, Zhang W, et al.
Front Microbiol
. 2023 Aug;
14:1211301.
PMID: 37601384
Fusarium wilt of banana (FWB) caused by f. sp. tropical race 4 ( TR4), poses a serious problem for sustainable banana production. Biological control is one of the effective measures...
19.
Xu S, Sun Y, Wang P, Tan Y, Shi L, Chen J
J Enzyme Inhib Med Chem
. 2023 Aug;
38(1):2247579.
PMID: 37587873
Angiogenesis plays an important role in tumour generation and progression, which is used to supply nutrients and metastasis. Herein, a series of novel dihydro-1-indene derivatives were designed and evaluated as...
20.
Xie S, Zhu J, Li J, Zhan F, Yao H, Xu J, et al.
J Med Chem
. 2023 Aug;
66(16):10917-10933.
PMID: 37535706
Targeted protein degradation (TPD) technologies have catalyzed a paradigm shift in therapeutic strategies and offer innovative avenues for drug design. Hydrophobic tags (HyTs) are bifunctional TPD molecules consisting of a...