Shengdi Fan
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Explore the profile of Shengdi Fan including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
186
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Recent Articles
1.
Liu J, Zhang L, Ma H, Sun H, Ge S, Liu J, et al.
Carbohydr Polym
. 2025 Jan;
352():123184.
PMID: 39843087
The limited membrane permeability and bacterial resistance pose significant challenges in the management of intracellular drug-resistant bacterial infections. To overcome this issue, we developed a bacterial-targeted drug delivery system based...
2.
Fan R, Shi X, Guo B, Zhao J, Liu J, Quan C, et al.
Protein Expr Purif
. 2020 Sep;
177:105765.
PMID: 32987120
The SaeRS two-component system in Staphylococcus aureus controls the expression of a series of virulence factors, such as hemolysins, proteases, and coagulase. The response regulator, SaeR, belongs to the OmpR...
3.
Zhang L, Quan C, Zhang X, Xiong W, Fan S
Chem Biol Drug Des
. 2019 Feb;
93(5):712-723.
PMID: 30737896
AgrC, as an integral membrane receptor protein with histidine kinase activity, is an important component of the agr quorum-sensing system of Staphylococcus aureus. AgrC acts as a sensor for the...
4.
Quan C, Liu J, Zhou W, Zheng W, Jin L, Zhao J, et al.
Sheng Wu Gong Cheng Xue Bao
. 2018 Feb;
34(2):235-245.
PMID: 29424137
Cyclic lipopeptide has extensive application prospect in the field of medicine due to its unique chemical structure and biological activity. This study aims to obtain high purity of cyclic lipopeptide...
5.
Xu Y, Jo I, Wang L, Chen J, Fan S, Dong Y, et al.
Biochem Biophys Res Commun
. 2017 Sep;
493(1):152-157.
PMID: 28917834
Membrane fusion proteins (MFPs) play an essential role in the action of the drug efflux pumps and protein secretion systems in bacteria. The sporulation delaying protein (SDP) efflux pump YknWXYZ...
6.
Xu Y, Wang L, Chen J, Zhao J, Fan S, Dong Y, et al.
Biochemistry
. 2017 Sep;
56(40):5347-5355.
PMID: 28862845
The Gram-negative, rod-shaped bacterium Aeromonas hydrophila has two multifunctional 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) enzymes, MtaN-1 and MtaN-2, that differ from those in other bacteria. These proteins are essential for several metabolic...
7.
Xu Y, Guo J, Wang L, Jiang R, Jin X, Liu J, et al.
PLoS One
. 2016 Jun;
11(5):e0155846.
PMID: 27243566
Bacillus possesses the peptide toxin Sporulation-Delaying Protein (SDP), which can kill cells within a biofilm to support continued growth, thereby delaying the onset of biofilm sporulation. The four-component transporter YknWXYZ...
8.
Jin L, Quan C, Hou X, Fan S
Mar Drugs
. 2016 Apr;
14(4).
PMID: 27110799
In recent years, a considerable number of structurally unique metabolites with biological and pharmacological activities have been isolated from the marine-derived fungi, such as polyketides, alkaloids, peptides, lactones, terpenoids and...
9.
Xu Y, Guo J, Jin X, Kim J, Ji Y, Fan S, et al.
BMC Struct Biol
. 2016 Feb;
16:3.
PMID: 26865045
Background: The universal stress proteins (USP) family member UspE is a tandem-type USP that consists of two Usp domains. The UspE expression levels of the Escherichia coli (E. coli) become...
10.
Xiong W, Quan C, Zhang X, Wang L, Liu B, Jin L, et al.
J Biosci Bioeng
. 2015 Nov;
121(2):242-6.
PMID: 26560241
AgrC is an integral membrane receptor protein with histidine kinase activity in the accessory gene regulator (agr) quorum-sensing system of Staphylococcus aureus. In this study, proteoliposomes were used as a...