Sheila A Baker
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Explore the profile of Sheila A Baker including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1048
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Recent Articles
1.
Hassan S, Hsu Y, Mayer S, Thomas J, Kothapalli A, Helms M, et al.
Saudi J Ophthalmol
. 2023 Dec;
37(4):313-320.
PMID: 38155679
Purpose: The purpose of this study was to develop a visually guided swim assay (VGSA) for measuring vision in mouse retinal disease models comparable to the multi-luminance mobility test (MLMT)...
2.
Inamdar S, Lankford C, Baker S
Adv Exp Med Biol
. 2023 Jul;
1415:269-276.
PMID: 37440044
Photoreceptors (PRs) in the neural retina convert photon capture into an electrical signal that is communicated across a chemical synapse to second-order neurons in the retina and on through the...
3.
Laird J, Kopel A, Lankford C, Baker S
Front Mol Neurosci
. 2023 May;
16:1155955.
PMID: 37181655
The voltage-gated calcium channel, Cav1.4 is localized to photoreceptor ribbon synapses and functions both in molecular organization of the synapse and in regulating release of synaptic vesicles. Mutations in Cav1.4 ...
4.
Scruggs B, Bhattarai S, Helms M, Cherascu I, Salesevic A, Stalter E, et al.
PLoS One
. 2022 Dec;
17(12):e0276298.
PMID: 36477475
Objective: To evaluate efficacy of a novel adeno-associated virus (AAV) vector, AAV2/4-RS1, for retinal rescue in the retinoschisin knockout (Rs1-KO) mouse model of X-linked retinoschisis (XLRS). Brinzolamide (Azopt®), a carbonic...
5.
Lankford C, Houtman J, Baker S
PLoS One
. 2022 Jun;
17(6):e0268335.
PMID: 35679272
Hyperpolarization activated cyclic nucleotide-gated channel 1 (HCN1) is expressed throughout the nervous system and is critical for regulating neuronal excitability, with mutations being associated with multiple forms of epilepsy. Adaptive...
6.
Lankford C, Umino Y, Poria D, Kefalov V, Solessio E, Baker S
J Neurosci
. 2022 Apr;
42(21):4231-4249.
PMID: 35437278
Signal integration of converging neural circuits is poorly understood. One example is in the retina where the integration of rod and cone signaling is responsible for the large dynamic range...
7.
Inamdar S, Lankford C, Poria D, Laird J, Solessio E, Kefalov V, et al.
Hum Mol Genet
. 2021 Oct;
31(7):1035-1050.
PMID: 34652420
Heteromeric Kv2.1/Kv8.2 channels are voltage-gated potassium channels localized to the photoreceptor inner segment. They carry IKx, which is largely responsible for setting the photoreceptor resting membrane potential. Mutations in Kv8.2...
8.
Lankford C, Laird J, Inamdar S, Baker S
Front Cell Neurosci
. 2020 Nov;
14:595523.
PMID: 33250719
Vision, hearing, smell, taste, and touch are the tools used to perceive and navigate the world. They enable us to obtain essential resources such as food and highly desired resources...
9.
Maddox J, Randall K, Yadav R, Williams B, Hagen J, Derr P, et al.
Elife
. 2020 Sep;
9.
PMID: 32940604
Synapses are fundamental information processing units that rely on voltage-gated Ca (Ca) channels to trigger Ca-dependent neurotransmitter release. Ca channels also play Ca-independent roles in other biological contexts, but whether...
10.
Laird J, Gardner S, Kopel A, Kerov V, Lee A, Baker S
Invest Ophthalmol Vis Sci
. 2019 Jul;
60(8):3150-3161.
PMID: 31335952
Purpose: Cav1.4 is a voltage-gated calcium channel clustered at the presynaptic active zones of photoreceptors. Cav1.4 functions in communication by mediating the Ca2+ influx that triggers neurotransmitter release. It also...