Shehrazade Dahimene
Overview
Explore the profile of Shehrazade Dahimene including associated specialties, affiliations and a list of published articles.
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16
Citations
371
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Recent Articles
1.
Dahimene S, Page K, Nieto-Rostro M, Pratt W, Dolphin A
Function (Oxf)
. 2023 Nov;
5(1):zqad060.
PMID: 38020068
N-type calcium channels (Ca2.2) are predominantly localized in presynaptic terminals, and are particularly important for pain transmission in the spinal cord. Furthermore, they have multiple isoforms, conferred by alternatively spliced...
2.
Page K, Gumerov V, Dahimene S, Zhulin I, Dolphin A
Channels (Austin)
. 2023 Feb;
17(1):2167563.
PMID: 36735378
In this hybrid review, we have first collected and reviewed available information on the structure and function of the enigmatic cache domains in αδ proteins. These are organized into two...
3.
Kadurin I, Dahimene S, Page K, Ellaway J, Chaggar K, Troeberg L, et al.
Function (Oxf)
. 2022 Apr;
3(3):zqac013.
PMID: 35462614
The auxiliary αδ subunits of voltage-gated calcium (Ca) channels are key to augmenting expression and function of Ca1 and Ca2 channels, and are also important drug targets in several therapeutic...
4.
Dahimene S, von Elsner L, Holling T, Mattas L, Pickard J, Lessel D, et al.
Brain
. 2022 Mar;
145(8):2721-2729.
PMID: 35293990
Voltage-gated calcium (CaV) channels form three subfamilies (CaV1-3). The CaV1 and CaV2 channels are heteromeric, consisting of an α1 pore-forming subunit, associated with auxiliary CaVβ and α2δ subunits. The α2δ...
5.
Meyer J, Dahimene S, Page K, Ferron L, Kadurin I, Ellaway J, et al.
Cell Rep
. 2019 Oct;
29(1):22-33.e5.
PMID: 31577951
Voltage-gated calcium channels are exquisitely Ca selective, conferred primarily by four conserved pore-loop glutamate residues contributing to the selectivity filter. There has been little previous work directly measuring whether the...
6.
Dahimene S, Page K, Kadurin I, Ferron L, Ho D, Powell G, et al.
Cell Rep
. 2018 Nov;
25(6):1610-1621.e5.
PMID: 30404013
Voltage-gated calcium channel auxiliary α2δ subunits are important for channel trafficking and function. Here, we compare the effects of α2δ-1 and an α2δ-like protein called Cachd1 on neuronal N-type (Ca2.2)...
7.
Dahimene S, Page K, Nieto-Rostro M, Pratt W, DArco M, Dolphin A
Neurobiol Dis
. 2016 Jun;
93:243-56.
PMID: 27260834
Episodic ataxia 2 (EA2) is an autosomal dominant disorder caused by mutations in the gene CACNA1A that encodes the pore-forming CaV2.1 calcium channel subunit. The majority of EA2 mutations reported...
8.
Heyes S, Pratt W, Rees E, Dahimene S, Ferron L, Owen M, et al.
Prog Neurobiol
. 2015 Sep;
134:36-54.
PMID: 26386135
This review summarises genetic studies in which calcium channel genes have been connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and schizophrenia to autism spectrum disorders and intellectual...
9.
Martins J, Kongsuphol P, Sammels E, Dahimene S, Aldehni F, Clarke L, et al.
Biochim Biophys Acta
. 2011 Sep;
1812(11):1385-92.
PMID: 21907281
In many cells, increase in intracellular calcium ([Ca(2+)](i)) activates a Ca(2+)-dependent chloride (Cl(-)) conductance (CaCC). CaCC is enhanced in cystic fibrosis (CF) epithelial cells lacking Cl(-) transport by the CF...
10.
Almaca J, Dahimene S, Appel N, Conrad C, Kunzelmann K, Pepperkok R, et al.
Methods Mol Biol
. 2011 May;
742:249-64.
PMID: 21547737
As several genomes have been sequenced, post-genomic approaches like transcriptomics and proteomics, identifying gene products differentially expressed in association with a given pathology, have held promise both of understanding the...