Shawn S-C Li
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Explore the profile of Shawn S-C Li including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1505
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Recent Articles
1.
Yaron-Barir T, Joughin B, Huntsman E, Kerelsky A, Cizin D, Cohen B, et al.
Nature
. 2024 May;
629(8014):1174-1181.
PMID: 38720073
Phosphorylation of proteins on tyrosine (Tyr) residues evolved in metazoan organisms as a mechanism of coordinating tissue growth. Multicellular eukaryotes typically have more than 50 distinct protein Tyr kinases that...
2.
Zeng P, Cecchini M, Barrett J, Shammas-Toma M, De Cecco L, Serafini M, et al.
EBioMedicine
. 2022 Nov;
86:104373.
PMID: 36442320
Background: There is significant interest in treatment de-escalation for human papillomavirus-associated (HPV) oropharyngeal squamous cell carcinoma (OPSCC) patients given the generally favourable prognosis. However, 15-30% of patients recur after primary...
3.
Qin L, Cao X, Kaneko T, Voss C, Liu X, Wang G, et al.
J Biol Chem
. 2021 Sep;
297(4):101161.
PMID: 34480897
Cell migration is an essential physiological process, and aberrant migration of epithelial cells underlies many pathological conditions. However, the molecular mechanisms governing cell migration are not fully understood. We report...
4.
Esmail S, Knauer M, Abdoh H, Voss C, Chin-Yee B, Stogios P, et al.
Cell Rep Methods
. 2021 Jul;
1(2):100011.
PMID: 34235498
We have developed a rapid, accurate, and cost-effective serologic test for SARS-CoV-2 virus, which caused the COVID-19 pandemic, on the basis of antibody-dependent agglutination of antigen-coated latex particles. When validated...
5.
Biggar K, Charih F, Liu H, Ruiz-Blanco Y, Stalker L, Chopra A, et al.
Cell Rep
. 2020 Jul;
32(2):107896.
PMID: 32668242
Protein Lys methylation plays a critical role in numerous cellular processes, but it is challenging to identify Lys methylation in a systematic manner. Here we present an approach combining in...
6.
Ming L, Zou Y, Zhao Y, Zhang L, He N, Chen Z, et al.
Proteomics
. 2020 Jul;
20(15-16):e2000061.
PMID: 32643287
A large number of post-translational modifications (PTMs) in proteins are buried in the unassigned mass spectrometric (MS) spectra in shot-gun proteomics datasets. Because the modified peptide fragments are low in...
7.
Esmail S, Li S
Structure
. 2019 Sep;
27(9):1352-1354.
PMID: 31484049
In this issue of Structure, Li et al. (2019) describe the structure of the MORN4-Myo3a complex, revealing that the MORN repeats in MORN4 form a single-layer antiparallel β sheet and...
8.
Liu H, Huang H, Voss C, Kaneko T, Qin W, Sidhu S, et al.
Mol Cell Proteomics
. 2018 Nov;
18(2):372-382.
PMID: 30482845
Src homology 2 (SH2) domains play an essential role in cellular signal transduction by binding to proteins phosphorylated on Tyr residue. Although Tyr phosphorylation (pY) is a prerequisite for binding...
9.
Kaneko T, Stogios P, Ruan X, Voss C, Evdokimova E, Skarina T, et al.
Nat Commun
. 2018 Nov;
9(1):4549.
PMID: 30382091
Src homology 2 (SH2) domains play a critical role in signal transduction in mammalian cells by binding to phosphorylated Tyr (pTyr). Apart from a few isolated cases in viruses, no...
10.
Balasuriya N, Kunkel M, Liu X, Biggar K, Li S, Newton A, et al.
J Biol Chem
. 2018 May;
293(27):10744-10756.
PMID: 29773654
The proto-oncogene Akt/protein kinase B (PKB) is a pivotal signal transducer for growth and survival. Growth factor stimulation leads to Akt phosphorylation at two regulatory sites (Thr-308 and Ser-473), acutely...