Shawn M Gillespie
Overview
Explore the profile of Shawn M Gillespie including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
7298
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Taylor K, Barron T, Hui A, Spitzer A, Yalcin B, Ivec A, et al.
Nature
. 2023 Nov;
623(7986):366-374.
PMID: 37914930
The role of the nervous system in the regulation of cancer is increasingly appreciated. In gliomas, neuronal activity drives tumour progression through paracrine signalling factors such as neuroligin-3 and brain-derived...
2.
Cho K, Gillespie S, Kalogriopoulos N, Quezada M, Jacko M, Monje M, et al.
Elife
. 2022 Mar;
11.
PMID: 35311648
Technologies for detecting cell-cell contacts are powerful tools for studying a wide range of biological processes, from neuronal signaling to cancer-immune interactions within the tumor microenvironment. Here, we report TRACC...
3.
Majzner R, Ramakrishna S, Yeom K, Patel S, Chinnasamy H, Schultz L, et al.
Nature
. 2022 Feb;
603(7903):934-941.
PMID: 35130560
Diffuse intrinsic pontine glioma (DIPG) and other H3K27M-mutated diffuse midline gliomas (DMGs) are universally lethal paediatric tumours of the central nervous system. We have previously shown that the disialoganglioside GD2...
4.
Gibson E, Bennett F, Gillespie S, Guler A, Gutmann D, Halpern C, et al.
Cell
. 2020 Jun;
181(7):1445-1449.
PMID: 32533917
The COVID19 crisis has magnified the issues plaguing academic science, but it has also provided the scientific establishment with an unprecedented opportunity to reset. Shoring up the foundation of academic...
5.
Lin G, Wilson K, Ceribelli M, Stanton B, Woo P, Kreimer S, et al.
Sci Transl Med
. 2019 Nov;
11(519).
PMID: 31748226
Diffuse midline gliomas (DMGs) are universally lethal malignancies occurring chiefly during childhood and involving midline structures of the central nervous system, including thalamus, pons, and spinal cord. These molecularly related...
6.
Anastas J, Zee B, Kalin J, Kim M, Guo R, Alexandrescu S, et al.
Cancer Cell
. 2019 Oct;
36(5):528-544.e10.
PMID: 31631026
H3K27M mutations resulting in epigenetic dysfunction are frequently observed in diffuse intrinsic pontine glioma (DIPGs), an incurable pediatric cancer. We conduct a CRISPR screen revealing that knockout of KDM1A encoding...
7.
Nagaraja S, Quezada M, Gillespie S, Arzt M, Lennon J, Woo P, et al.
Mol Cell
. 2019 Oct;
76(6):965-980.e12.
PMID: 31588023
Development of effective targeted cancer therapies is fundamentally limited by our molecular understanding of disease pathogenesis. Diffuse intrinsic pontine glioma (DIPG) is a fatal malignancy of the childhood pons characterized...
8.
Venkatesh H, Morishita W, Geraghty A, Silverbush D, Gillespie S, Arzt M, et al.
Nature
. 2019 Sep;
573(7775):539-545.
PMID: 31534222
High-grade gliomas are lethal brain cancers whose progression is robustly regulated by neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but this alone is insufficient to explain the...
9.
Karaayvaz M, Cristea S, Gillespie S, Patel A, Mylvaganam R, Luo C, et al.
Nat Commun
. 2018 Sep;
9(1):3588.
PMID: 30181541
Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by extensive intratumoral heterogeneity. To investigate the underlying biology, we conducted single-cell RNA-sequencing (scRNA-seq) of >1500 cells from six primary TNBC....
10.
Ryan R, Petrovic J, Rausch D, Zhou Y, Lareau C, Kluk M, et al.
Cell Rep
. 2017 Oct;
21(3):784-797.
PMID: 29045844
Gain-of-function Notch mutations are recurrent in mature small B cell lymphomas such as mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL), but the Notch target genes that contribute to...