Sharad K Mittal
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Explore the profile of Sharad K Mittal including associated specialties, affiliations and a list of published articles.
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39
Citations
693
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Recent Articles
1.
Wagh V, Damodaren N, Mittal S, Cardenas-Diaz F, Sun H, Loktev A, et al.
Adv Exp Med Biol
. 2025 Feb;
1468:33-37.
PMID: 39930169
Age-related macular degeneration (AMD) is the leading cause of blindness in the aged population. The accumulation of abnormal extracellular drusen deposits between the retinal pigment epithelium (RPE) and Bruch's membrane...
2.
Folorunso O, Sinha N, Singh A, Xi L, Pulimamidi V, Cho W, et al.
Am J Pathol
. 2024 Dec;
PMID: 39732392
Tissue inhibitors of metalloproteinases (TIMPs) modulate extracellular matrix remodeling for maintaining homeostasis and promoting cell migration and proliferation. Pathologic conditions can alter TIMP homeostasis and aggravate disease progression. The roles...
3.
Lee M, Elbasiony E, Cho W, Pulimamidi V, Folorunso O, Mittal S, et al.
Sci Rep
. 2024 Nov;
14(1):26421.
PMID: 39488561
Different therapeutic modalities, including steroids, have been used to treat corneal scarring. However, the ability of steroids to reduce corneal scarring is limited and associated with numerous side effects. Our...
4.
Cho W, Pulimamidi V, Mittal S, Chauhan S
FASEB J
. 2024 May;
38(10):e23683.
PMID: 38758184
Mesenchymal stromal cells (MSCs) have been shown to modulate the function of various subsets of T cells such as naïve CD4 T cells and IFNγCD4 Th1 cells; however, mechanisms underlying...
5.
Wang S, Mittal S, Lee S, Herrera A, Krauthammer M, Elbasiony E, et al.
Invest Ophthalmol Vis Sci
. 2024 Jan;
65(1):40.
PMID: 38261311
Purpose: To evaluate whether fibrosis contributes to corneal transplant failure and to determine whether effector CD4+ T cells, the key immune cells in corneal transplant rejection, play a direct role...
6.
Singh A, Cho W, Pulimamidi V, Mittal S, Chauhan S
Invest Ophthalmol Vis Sci
. 2023 Nov;
64(14):1.
PMID: 37910094
Purpose: Regulation of inflammation is critical for achieving favorable outcomes in wound healing. In this study, we determine the functional role and mechanism of action of IL-11, an immunomodulatory cytokine,...
7.
Cho W, Mittal S, Chauhan S
Stem Cells Transl Med
. 2023 Mar;
12(4):221-233.
PMID: 36972356
Mounting evidence suggests mesenchymal stromal cells (MSCs) suppress CD4+ T-cell activation, but whether MSCs directly regulate activation and expansion of allogeneic T cells has not been fully deciphered. Here, we...
8.
Elbasiony E, Cho W, Singh A, Mittal S, Zoukhri D, Chauhan S
NPJ Aging
. 2023 Feb;
9(1):2.
PMID: 36849524
The lacrimal gland undergoes significant structural and functional deterioration with aging. Marked with increased inflammation and fibrosis, the aged lacrimal gland is unable to perform its protective function. As a...
9.
Cho W, Elbasiony E, Singh A, Mittal S, Chauhan S
Am J Pathol
. 2023 Feb;
193(11):1740-1749.
PMID: 36740182
Prevention of inflammatory angiogenesis is critical for suppressing chronic inflammation and inhibiting inflammatory tissue damage. Angiogenesis is particularly detrimental to the cornea because pathologic growth of new blood vessels can...
10.
Shukla S, Cho W, Elbasiony E, Singh R, Mittal S, Chauhan S
FASEB J
. 2022 Jul;
36(8).
PMID: 35781326
Regulation of innate inflammation is critical for maintaining tissue homeostasis and barrier function, especially in those interfacing the external environments such as the skin and cornea. Expression of pro-inflammatory cytokines...