Shaoxun Wang
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Explore the profile of Shaoxun Wang including associated specialties, affiliations and a list of published articles.
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35
Citations
519
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Recent Articles
11.
Jiang B, Wang S, Song G, Jiang Q, Fan M, Fang C, et al.
Sci Signal
. 2023 Mar;
16(777):eabo3406.
PMID: 36943921
The zinc finger protein ZFYVE21 is involved in immune signaling. Using humanized mouse models, primary human cells, and patient samples, we identified a T cell-autonomous role for ZFYVE21 in promoting...
12.
Wang S, Tang C, Liu Y, Border J, Roman R, Fan F
Front Aging
. 2022 Dec;
3:1077302.
PMID: 36531742
Although the causes of cognitive impairment are multifactorial, emerging evidence indicates that cerebrovascular dysfunction plays an essential role in dementia. One of the most critical aspects of cerebrovascular dysfunction is...
13.
Nielsen C, Zhang X, Raygor K, Wang S, Bollen A, Wang R
J Exp Med
. 2022 Nov;
220(2).
PMID: 36441145
Upregulation of Notch signaling is associated with brain arteriovenous malformation (bAVM), a disease that lacks pharmacological treatments. Tetracycline (tet)-regulatable endothelial expression of constitutively active Notch4 (Notch4*tetEC) from birth induced bAVMs...
14.
Song G, Wang S, Barkestani M, Mullan C, Fan M, Jiang B, et al.
Front Immunol
. 2022 Oct;
13:1020889.
PMID: 36211400
Endothelial cells (ECs) form a critical immune interface regulating both the activation and trafficking of alloreactive T cells. In the setting of solid organ transplantation, donor-derived ECs represent sites where...
15.
Wang S, Jiao F, Border J, Fang X, Crumpler R, Liu Y, et al.
Am J Physiol Heart Circ Physiol
. 2021 Dec;
322(2):H246-H259.
PMID: 34951541
Diabetes mellitus (DM) is a leading risk factor for age-related dementia, but the mechanisms involved are not well understood. We previously discovered that hyperglycemia induced impaired myogenic response (MR) and...
16.
Gonzalez-Fernandez E, Fan L, Wang S, Liu Y, Gao W, Thomas K, et al.
Physiol Genomics
. 2021 Dec;
54(2):58-70.
PMID: 34859687
Hypertension is a leading risk factor for stroke, heart disease, chronic kidney disease, vascular cognitive impairment, and Alzheimer's disease. Previous genetic studies have nominated hundreds of genes linked to hypertension,...
17.
Jiao F, Varghese K, Wang S, Liu Y, Yu H, Booz G, et al.
J Cardiovasc Pharmacol
. 2021 May;
77(6):728-734.
PMID: 34001724
The monoterpene glycoside paeoniflorin (PF) is the principal active constituent of the traditional Chinese herbal medicines, Radix Paeoniae Alba and Radix Paeoniae Rubra, which have been used for millennia to...
18.
Shekhar S, Liu Y, Wang S, Zhang H, Fang X, Zhang J, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33669830
Ischemic stroke is one of the most disabling diseases and a leading cause of death globally. Despite advances in medical care, the global burden of stroke continues to grow, as...
19.
Wang S, Roman R, Fan F
J Neurobiol Physiol
. 2020 Dec;
2(1):15-18.
PMID: 33336208
Individuals with spinal cord injury (SCI) have a significantly increased risk for cognitive impairment that is associated with cerebrovascular remodeling and endothelial dysfunction. The sub-acute stage following high thoracic SCI...
20.
Gao W, Liu Y, Fan L, Zheng B, Jefferson J, Wang S, et al.
Am J Physiol Renal Physiol
. 2020 Dec;
320(1):F97-F113.
PMID: 33308016
We recently reported that the enhanced susceptibility to chronic kidney disease (CKD) in the fawn-hooded hypertensive (FHH) rat is caused, at least in part, by a mutation in γ-adducin (ADD3)...