Shaoxun Wang
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Explore the profile of Shaoxun Wang including associated specialties, affiliations and a list of published articles.
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35
Citations
519
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Recent Articles
1.
Tang C, Border J, Zhang H, Gregory A, Bai S, Fang X, et al.
Geroscience
. 2025 Feb;
PMID: 39903369
Alzheimer's Disease and Alzheimer's Disease-related dementias (AD/ADRD) pose major global healthcare challenges, with diabetes mellitus (DM) being a key risk factor. Both AD and DM-related ADRD are characterized by reduced...
2.
Tang C, Border J, Zhang H, Gregory A, Bai S, Fang X, et al.
bioRxiv
. 2024 Sep;
PMID: 39257786
Alzheimer's Disease and Alzheimer's Disease-related dementias (AD/ADRD) pose major global healthcare challenges, with diabetes mellitus (DM) being a key risk factor. Both AD and DM-related ADRD are characterized by reduced...
3.
Jane-Wit D, Song G, He L, Jiang Q, Barkestani M, Wang S, et al.
Res Sq
. 2024 Jul;
PMID: 38947095
Internalized pools of membrane attack complexes (MACs) promote NF-kB and dysregulated tissue inflammation. Here, we show that C9, a MAC-associated protein, promotes loss of proteostasis to become intrinsically immunogenic. Surface-bound...
4.
Jiang Q, Song G, He L, Li X, Jiang B, Wang Q, et al.
Kidney Int
. 2024 May;
106(3):419-432.
PMID: 38797325
ZFYVE21 is an ancient, endosome-associated protein that is highly expressed in endothelial cells (ECs) but whose function(s) in vivo are undefined. Here, we identified ZFYVE21 as an essential regulator of...
5.
Li X, Jiang Q, Song G, Barkestani M, Wang Q, Wang S, et al.
Nat Commun
. 2023 Dec;
14(1):8404.
PMID: 38110370
No abstract available.
6.
Wang S, Song G, Barkestani M, Tobiasova Z, Wang Q, Jiang Q, et al.
Front Immunol
. 2023 Nov;
14:1248027.
PMID: 37915586
Introduction: Ischemia reperfusion injury (IRI) confers worsened outcomes and is an increasing clinical problem in solid organ transplantation. Previously, we identified a "Ptch" T-cell subset that selectively received costimulatory signals...
7.
Zhang H, Border J, Fang X, Liu Y, Tang C, Gao W, et al.
J Pharm Pharmacol Res
. 2023 Aug;
7(2):49-61.
PMID: 37588944
Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) are neurodegenerative disorders. Recent studies suggest that cerebral hypoperfusion is an early symptom of AD/ADRD. Dual-specificity protein phosphatase 5 (DUSP5) has been...
8.
Li X, Jiang Q, Song G, Barkestani M, Wang Q, Wang S, et al.
Nat Commun
. 2023 Jun;
14(1):3336.
PMID: 37286577
No abstract available.
9.
Huang L, Cheng F, Zhang X, Zielonka J, Nystoriak M, Xiang W, et al.
Sci Adv
. 2023 May;
9(21):eade7280.
PMID: 37235659
Mechanisms underlying arteriovenous malformations (AVMs) are poorly understood. Using mice with endothelial cell (EC) expression of constitutively active Notch4 (Notch4*), we show decreased arteriolar tone in vivo during brain AVM...
10.
Li X, Jiang Q, Song G, Barkestani M, Wang Q, Wang S, et al.
Nat Commun
. 2023 May;
14(1):3002.
PMID: 37225719
Internalization of complement membrane attack complexes (MACs) assembles NLRP3 inflammasomes in endothelial cells (EC) and promotes IL-β-mediated tissue inflammation. Informed by proteomics analyses of FACS-sorted inflammasomes, we identify a protein...