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Shaoshun Li

Explore the profile of Shaoshun Li including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 266
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Recent Articles
1.
Wu Z, Shi T, Shao Q, Chen D, Gao P, Wang J, et al.
Mol Pharm . 2025 Jan; 22(3):1507-1517. PMID: 39885683
Early detection and precise treatment for breast cancer are crucial, given its high global incidence rate. Hence, the development of novel imaging targets is essential for diagnosing and monitoring resistance...
2.
Chen D, Li R, Shao Q, Wu Z, Cui J, Meng Q, et al.
J Med Chem . 2023 Nov; 66(23):16032-16050. PMID: 38031326
Cytochrome P450 1B1 (CYP1B1) is induced during the early stage of cancer and is universally overexpressed in tumors. Thus, it was considered as a potential biomarker for the monitoring of...
3.
Wu L, Cui J, Zhao C, Wang Z, Lu J, Li S, et al.
J Med Chem . 2023 Jun; 66(12):8011-8029. PMID: 37272653
Bombesin receptor subtype-3 (BB, BRS-3) is an orphan G protein-coupled receptor. The characterization of novel synthetic ligands for BB is an alternative and attractive strategy to study its diverse physiological...
4.
Wang Z, Chen D, Fan Q, Wu Z, Dong J, Cui J, et al.
Chembiochem . 2022 May; 23(14):e202200268. PMID: 35567365
Cytochrome P450 (CYP) 1B1 has been found to be overexpressed specifically in tumor tissues at an early stage, which makes it a potential cancer biomarker for molecular imaging. Multimodal imaging...
5.
Dong J, Wang Z, Meng Q, Zhang Q, Huang G, Cui J, et al.
RSC Adv . 2022 May; 8(27):15009-15020. PMID: 35541321
The CYP1B1 enzyme is regarded as a potential target for cancer prevention and therapy. Based on the structure of α-naphthoflavone (ANF), diverse 2-arylbenzo[]quinolone derivatives were designed, synthesized and evaluated as...
6.
Chen D, Fan Q, Xu T, Dong J, Cui J, Wang Z, et al.
Anticancer Agents Med Chem . 2021 Apr; 22(2):261-269. PMID: 33820523
Background: Cytochrome P450 1B1 (CYP1B1) is specifically expressed in a variety of tumors which makes it a promising imaging target of tumor. Objective: We aimed to design and synthesize CYP1B1...
7.
Qian J, Cui J, Li S, Chen J, Jia J
Mini Rev Med Chem . 2021 Jan; 21(12):1465-1486. PMID: 33438535
Background: Multidrug resistance (MDR) is the resistance of cancer cells against a variety of currently used antineoplastic agents with diverse structural scaffolds and different anticancer mechanisms. It has been recognized...
8.
Dong J, Huang G, Cui Q, Meng Q, Li S, Cui J
Eur J Med Chem . 2020 Oct; 209:112895. PMID: 33069055
Cytochrome P450 1B1 (CYP1B1) has been well validated as an attractive target for cancer prevention and drug resistance reversal. In continuation of our interest in this area, herein, a set...
9.
Cui J, Li S, Jia J
Nat Prod Res . 2020 May; 36(1):18-25. PMID: 32375516
7-Methyl juglone as a naturally occurring naphthoquinone showed striking antibacterial, antifungal, antivirus and anticancer activity. Its derivatives had also been characterized as key intermediates in the preparation of natural naphthoquinones...
10.
Dong J, Wang Z, Cui J, Meng Q, Li S
Eur J Med Chem . 2019 Dec; 187:111938. PMID: 31830634
Cytochrome P450 1B1(CYP1B1) has been recognized as an important target for cancer prevention and drug resistance reversal. In order to obtain potent and selective CYP1B1 inhibitors, a series of forty-one...