Shangara S Dehal
Overview
Explore the profile of Shangara S Dehal including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
141
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0
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Recent Articles
1.
Stresser D, Perloff E, Mason A, Blanchard A, Dehal S, Creegan T, et al.
Drug Metab Dispos
. 2016 May;
44(8):1424-30.
PMID: 27149898
The sedative clomethiazole (CMZ) has been used in Europe since the mid-1960s to treat insomnia and alcoholism. It has been previously demonstrated in clinical studies to reversibly inhibit human CYP2E1...
2.
Stresser D, Mason A, Perloff E, Ho T, Crespi C, Dandeneau A, et al.
Drug Metab Dispos
. 2009 Jan;
37(4):695-8.
PMID: 19144769
Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha, (-trifluoro-p-tolyl)oxy]-propylamine)] a selective serotonin reuptake inhibitor, is widely used in treating depression and other serotonin-dependent disease conditions. Racemic, (R)- and (S)-fluoxetine are potent reversible inhibitors of CYP2D6,...
3.
Dehal S
Drug Metab Rev
. 2006 May;
38(1-2):13-22.
PMID: 16684645
I worked with the late Dr. David Kupfer for nearly nine years at the Worcester Foundation/University of Massachusetts Medical School, Worcester, MA. I was involved in the metabolism of methoxychlor...
4.
Zhang J, Dehal S, Ho T, Johnson J, Chandler C, Blanchard A, et al.
Drug Metab Dispos
. 2006 Feb;
34(5):734-7.
PMID: 16501008
Clevidipine is a short-acting dihydropyridine calcium channel antagonist under development for treatment of perioperative hypertension. Patients treated with clevidipine are likely to be comedicated. Therefore, the potential for clevidipine and...
5.
Zhang D, Chando T, Everett D, Patten C, Dehal S, Humphreys W
Drug Metab Dispos
. 2005 Aug;
33(11):1729-39.
PMID: 16118329
Several human immunodeficiency virus (HIV) protease inhibitors, including atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir, were tested for their potential to inhibit uridine 5'-diphospho-glucuronosyltransferase (UGT) activity. Experiments were performed with...
6.
Stresser D, Broudy M, Ho T, Cargill C, Blanchard A, Sharma R, et al.
Drug Metab Dispos
. 2004 Jan;
32(1):105-12.
PMID: 14709627
Azamulin [14-O-(5-(2-amino-1,3,4-triazolyl)thioacetyl)-dihydromutilin] is an azole derivative of the pleuromutilin class of antiinfectives. We tested the inhibition potency of azamulin toward 18 cytochromes P450 using human liver microsomes or microsomes from...