Shang-Fu Chen
Overview
Explore the profile of Shang-Fu Chen including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
229
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Recent Articles
1.
Khattab A, Chen S, Wineinger N, Torkamani A
bioRxiv
. 2024 Jul;
PMID: 39071377
Background: The All of Us (AoU) Research Program provides a comprehensive genomic dataset to accelerate health research and medical breakthroughs. Despite its potential, researchers face significant challenges, including high costs...
2.
Torkamani A, Chen S, Lee S, Sadaei H, Park J, Khattab A, et al.
Res Sq
. 2024 Jan;
PMID: 38196609
Coronary artery disease (CAD) remains the leading cause of mortality and morbidity worldwide. Recent advances in large-scale genome-wide association studies have highlighted the potential of genetic risk, captured as polygenic...
3.
Sadaei H, Cordova-Palomera A, Lee J, Padmanabhan J, Chen S, Wineinger N, et al.
NPJ Parkinsons Dis
. 2022 Oct;
8(1):143.
PMID: 36302787
Parkinson's disease (PD) treatments modify disease symptoms but have not been shown to slow progression, characterized by gradual and varied motor and non-motor changes overtime. Variation in PD progression hampers...
4.
Dias R, Evans D, Chen S, Chen K, Loguercio S, Chan L, et al.
Elife
. 2022 Sep;
11.
PMID: 36148981
Genotype imputation is a foundational tool for population genetics. Standard statistical imputation approaches rely on the co-location of large whole-genome sequencing-based reference panels, powerful computing environments, and potentially sensitive genetic...
5.
Muse E, Chen S, Liu S, Fernandez B, Schrader B, Molparia B, et al.
NPJ Digit Med
. 2022 Mar;
5(1):30.
PMID: 35277577
We developed a smartphone application, MyGeneRank, to conduct a prospective observational cohort study (NCT03277365) involving the automated generation, communication, and electronic capture of response to a polygenic risk score (PRS)...
6.
Miao L, Chen S, Hsu Y, Hua K
Sensors (Basel)
. 2022 Jan;
22(2).
PMID: 35062647
Accidents are continuously reported for autonomous driving vehicles including those with advanced sensors installed. Some of accidents are usually caused by bad weather, poor lighting conditions and non-line-of-sight obstacles. Cellular...
7.
Muse E, Chen S, Torkamani A
Curr Cardiol Rep
. 2021 Jul;
23(8):107.
PMID: 34196841
Purpose Of The Review: Coronary artery disease (CAD) is a common disease globally attributable to the interplay of complex genetic and lifestyle factors. Here, we review how genomic sequencing advances...
8.
Chen S, Dias R, Evans D, Salfati E, Liu S, Wineinger N, et al.
Genome Med
. 2020 Nov;
12(1):100.
PMID: 33225976
Background: Polygenic risk scores (PRSs) are a summarization of an individual's genetic risk for a disease or trait. These scores are being generated in research and commercial settings to study...
9.
Hou S, Chen J, Song M, Zhu Y, Jan Y, Chen S, et al.
ACS Nano
. 2017 Nov;
11(12):12863.
PMID: 29160690
No abstract available.
10.
Wang C, Yang S, Hsu S, Chang F, Lin Y, Chen S, et al.
Free Radic Biol Med
. 2017 Oct;
113:439-451.
PMID: 29054545
Glutathione (GSH), the major non-enzymatic antioxidant, plays a critical role in cellular reactive oxygen species (ROS) neutralization. Moreover, GSH is required for the self-renewal maintenance of human embryonic stem cells...