Shane P C Mitchell
Overview
Explore the profile of Shane P C Mitchell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
8
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Perrin F, Anderson L, Mitchell S, Sinha P, Turchyna Y, Maesako M, et al.
Acta Neuropathol Commun
. 2024 Oct;
12(1):166.
PMID: 39434170
The recently discovered interaction between presenilin 1 (PS1), a subunit of γ-secretase involved in amyloid-β (Aβ) peptide production, and GLT-1, the major brain glutamate transporter (EAAT2 in the human), may...
2.
Perrin F, Anderson L, Mitchell S, Sinha P, Turchyna Y, Maesako M, et al.
Res Sq
. 2023 Nov;
PMID: 37986905
The recently discovered interaction between presenilin 1 (PS1), a catalytic subunit of γ-secretase responsible for the generation of amyloid-β(Aβ) peptides, and GLT-1, the major glutamate transporter in the brain (EAAT2...
3.
Houser M, Mitchell S, Sinha P, Lundin B, Berezovska O, Maesako M
Sensors (Basel)
. 2023 Mar;
23(5).
PMID: 36904854
Our unique multiplexed imaging assays employing FRET biosensors have previously detected that γ-secretase processes APP C99 primarily in late endosomes and lysosomes in live/intact neurons. Moreover we have shown that...
4.
Amodeo M, Mitchell S, Pavan V, Kuehner J
G3 (Bethesda)
. 2022 Oct;
13(1).
PMID: 36315099
Premature transcription termination (i.e. attenuation) is a potent gene regulatory mechanism that represses mRNA synthesis. Attenuation of RNA polymerase II is more prevalent than once appreciated, targeting 10-15% of mRNA...
5.
McKendell A, Houser M, Mitchell S, Wolfe M, Berezovska O, Maesako M
Biosensors (Basel)
. 2022 Aug;
12(8).
PMID: 36005059
Amyloid-beta (Aβ) peptides are produced within neurons. Some peptides are released into the brain parenchyma, while others are retained inside the neurons. However, the detection of intracellular Aβ remains a...