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Shane M Colley

Explore the profile of Shane M Colley including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 250
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Recent Articles
1.
Colley S, Wintle L, Searles R, Russell V, Firman R, Smith S, et al.
PLoS One . 2013 Aug; 8(8):e70700. PMID: 23976951
Nuclear receptors (NRs) and their coregulators play fundamental roles in initiating and directing gene expression influencing mammalian reproduction, development and metabolism. SRA stem Loop Interacting RNA-binding Protein (SLIRP) is a...
2.
Redfern A, Colley S, Beveridge D, Ikeda N, Epis M, Li X, et al.
Proc Natl Acad Sci U S A . 2013 Apr; 110(16):6536-41. PMID: 23550157
The cytoplasmic RNA-induced silencing complex (RISC) contains dsRNA binding proteins, including protein kinase RNA activator (PACT), transactivation response RNA binding protein (TRBP), and Dicer, that process pre-microRNAs into mature microRNAs...
3.
Colley S, Leedman P
Biochimie . 2011 Aug; 93(11):1966-72. PMID: 21807064
Steroid Receptor RNA Activator (SRA) occupies a unique and enigmatic position within the nuclear receptor (NR) field and more broadly in transcriptional regulation. This is as a result of its...
4.
Colley S, Leedman P
Crit Rev Biochem Mol Biol . 2009 Mar; 44(1):25-33. PMID: 19280430
The discovery that SRA RNA can function as a nuclear receptor (NR) coactivator resulted in a fundamental change in the perception of how NRs and their coregulators may regulate hormone...
5.
Colley S, Iyer K, Leedman P
IUBMB Life . 2008 Apr; 60(3):159-64. PMID: 18380007
Nuclear receptor (NR) coregulators are key modulators of hormone signaling. Discovery of steroid receptor RNA activator (SRA), a coregulator that is active as a RNA, transformed thinking in the field...
6.
Hatchell E, Colley S, Beveridge D, Epis M, Stuart L, Giles K, et al.
Mol Cell . 2006 Jun; 22(5):657-68. PMID: 16762838
Steroid receptor RNA activator (SRA), the only known RNA coactivator, augments transactivation by nuclear receptors (NRs). We identified SLIRP (SRA stem-loop interacting RNA binding protein) binding to a functional substructure...
7.
Ong D, Colley S, Norman M, Kitazawa S, Tobias J
J Bone Miner Res . 2004 Mar; 19(3):447-54. PMID: 15040833
Unlabelled: The effects of 17beta-estradiol (E2) and ICI 182,780 (ICI) on activity of a BMP-6 promoter were compared in osteoblast-like and breast cancer cells transiently transfected with ERalpha. E2 but...
8.
McDougall K, Perry M, Gibson R, Colley S, Korach K, Tobias J
Endocrinology . 2003 Apr; 144(5):1994-9. PMID: 12697707
We examined whether estrogen receptor (ER)alpha is required for estrogen to stimulate cancellous bone formation in long bones of male mice. 17 beta-Estradiol (E(2)) was administered to ER alpha(-/-) male...